Seriously cilia: A tiny organelle illuminates evolution, disease, and intercellular communication

C Derderian, GI Canales, JF Reiter - Developmental cell, 2023 - cell.com
The borders between cell and developmental biology, which have always been permeable,
have largely dissolved. One manifestation is the blossoming of cilia biology, with cell and …

[HTML][HTML] Zoonotic parasites associated with predation by dogs and cats

JA Mendoza Roldan, D Otranto - Parasites & Vectors, 2023 - Springer
One of the most common behaviors of cats that have an indoor/outdoor lifestyle is to bring
hunted “gifts” to their owners, represented by small mammals, reptiles and birds. Access to …

On the limits of fitting complex models of population history to f-statistics

R Maier, P Flegontov, O Flegontova, P Changmai… - Elife, 2023 - elifesciences.org
Our understanding of population history in deep time has been assisted by fitting admixture
graphs (AGs) to data: models that specify the ordering of population splits and mixtures …

[HTML][HTML] Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture

JRS Meadows, JM Kidd, GD Wang, HG Parker… - Genome biology, 2023 - Springer
Abstract Background The international Dog10K project aims to sequence and analyze
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …

From high masked to high realized genetic load in inbred Scandinavian wolves

L Smeds, H Ellegren - Molecular Ecology, 2023 - Wiley Online Library
When new mutations arise at functional sites they are more likely to impair than improve
fitness. If not removed by purifying selection, such deleterious mutations will generate a …

[PDF][PDF] Domestic dog lineages reveal genetic drivers of behavioral diversification

EV Dutrow, JA Serpell, EA Ostrander - Cell, 2022 - cell.com
Selective breeding of domestic dogs has generated diverse breeds often optimized for
performing specialized tasks. Despite the heritability of breed-typical behavioral traits …

[HTML][HTML] Modeling of African population history using f-statistics is biased when applying all previously proposed SNP ascertainment schemes

P Flegontov, U Işıldak, R Maier, E Yüncü… - Plos …, 2023 - journals.plos.org
f-statistics have emerged as a first line of analysis for making inferences about demographic
history from genome-wide data. Not only are they guaranteed to allow robust tests of the fits …

[HTML][HTML] Dog breeds and conformations in the UK in 2019: VetCompass canine demography and some consequent welfare implications

DG O'Neill, KM McMillan, DB Church, DC Brodbelt - PLoS One, 2023 - journals.plos.org
Introduction Growing concerns over health and welfare impacts from extreme phenotypes in
dogs have created an urgent need for reliable demographic information on the national …

[PDF][PDF] Tracing eastern wolf origins from whole-genome data in context of extensive hybridization

ST Vilaça, ME Donaldson, A Benazzo… - Molecular Biology …, 2023 - academic.oup.com
Southeastern Canada is inhabited by an amalgam of hybridizing wolf-like canids, raising
fundamental questions regarding their taxonomy, origins, and timing of hybridization events …

[HTML][HTML] Possible origins and implications of atypical morphologies and domestication-like traits in wild golden jackals (Canis aureus)

A Barash, S Preiss-Bloom, Y Machluf, E Fabbri… - Scientific Reports, 2023 - nature.com
Deciphering the origins of phenotypic variations in natural animal populations is a
challenging topic for evolutionary and conservation biologists. Atypical morphologies in …