Surfactant protein D in respiratory and non-respiratory diseases

GL Sorensen - Frontiers in medicine, 2018 - frontiersin.org
Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …

[HTML][HTML] Functional regulation of decidual macrophages during pregnancy

F Sun, S Wang, M Du - Journal of reproductive immunology, 2021 - Elsevier
A successful pregnancy requires that the maternal immune system recognizes and tolerates
the semi-allogeneic fetus without compromising the capability of protecting both mother and …

Is human labor at term an inflammatory condition?

C Kyathanahalli, M Snedden, E Hirsch - Biology of reproduction, 2023 - academic.oup.com
Parturition at term in normal pregnancy follows a predictable sequence of events. There is
some evidence that a state of inflammation prevails in the reproductive tissues during labor …

Non-pulmonary immune functions of surfactant proteins A and D

S Ujma, WGC Horsnell, AA Katz, HW Clark… - Journal of innate …, 2017 - karger.com
Abstract Surfactant proteins A (SP-A) and D (SP-D) are established as essential components
of our innate immune system for protecting the lung from pathogens and allergens. They …

Disruption of the SP-A/SP-R210L (MYO18Aα) pathway prolongs gestation and reduces fetal survival during lipopolysaccharide-induced parturition in late gestation

Z Guan, B Worth, TM Umstead… - … of Physiology-Lung …, 2024 - journals.physiology.org
Prolonged labor can lead to infection, fetal distress, asphyxia, and life-threatening harm to
both the mother and the baby. Surfactant protein A (SP-A) was shown to contribute to the …

Surfactant protein a impairs genital HPV16 pseudovirus infection by innate immune cell activation in a murine model

S Ujma, S Carse, A Chetty, W Horsnell, H Clark… - Pathogens, 2019 - mdpi.com
Infection by oncogenic human papillomavirus (HPV) is the principle cause of cervical cancer
and other anogenital cancers. The majority of cervical cancer cases occur in low-and middle …

[HTML][HTML] Role of collectins and complement protein C1q in pregnancy and parturition

SP Madhukaran, FS Alhamlan, K Kale, M Vatish… - Immunobiology, 2016 - Elsevier
Collectins such as surfactant proteins SP-A, SP-D, and mannan-binding lectin (MBL), as well
as complement protein C1q are evolutionarily conserved innate immune molecules. They …

Going Full TeRM: The Seminal Role of Tissue-Resident Macrophages in Organ Remodeling during Pregnancy and Lactation

Y Wu, YC Teh, SZ Chong - The Journal of Immunology, 2024 - journals.aai.org
During pregnancy and lactation, the uterus and mammary glands undergo remarkable
structural changes to perform their critical reproductive functions before reverting to their …

The collectin subfamily member 11 (Ca-Colec11) from Qihe crucian carp (Carassius auratus) agglutinates and inhibits Aeromonas hydrophila and Staphylococcus …

L Wang, Y Yu, L Wang, Q Wang, Y Zhang, P Gao… - Fish & Shellfish …, 2023 - Elsevier
The collectin subfamily member 11 (Colec11), plays an important role in innate immunity as
a pattern recognition molecule. In the present study, a colec11 homolog was identified and …

Fertility defects in surfactant associated protein D knockout female mice: altered ovarian hormone profile

S Kay, T Madan - Molecular Immunology, 2016 - Elsevier
Surfactant associated protein D (SFTPD, also known as SP-D), a pattern recognition
molecule, is an integral component of the mucosal immune system of female reproductive …