HR+, HER2-advanced breast cancer and CDK4/6 inhibitors: mode of action, clinical activity, and safety profiles

SL Sammons, DL Topping… - Current cancer drug …, 2017 - ingentaconnect.com
Background: Cyclin-dependent kinase (CDK) 4/6 inhibitor-based therapies have shown
great promise in improving clinical outcomes for patients with hormone receptor-positive …

Pulmonary embolism and in situ pulmonary artery thrombosis in paediatrics

M Rajpurkar, TT Biss, EK Amankwah… - Thrombosis and …, 2017 - thieme-connect.com
Data on paediatric pulmonary embolism (PE) are scarce. We sought to systematically review
the current literature on childhood PE and conducted a search on paediatric PE via PubMed …

Prothrombotic fibrin clot phenotype is associated with recurrent pulmonary embolism after discontinuation of anticoagulant therapy

M Zabczyk, K Plens, W Wojtowicz… - … , and Vascular Biology, 2017 - Am Heart Assoc
Objective—Pulmonary embolism (PE) is a life-threatening manifestation of venous
thromboembolism with a high recurrence rate after anticoagulation cessation. Recently, we …

[HTML][HTML] Current endovascular treatment options in acute pulmonary embolism

K Moore, J Kunin, M Alnijoumi, P Nagpal… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
Acute pulmonary embolism (PE) is a significant cause of mortality and morbidity across the
globe. Over the last few decades, there have been major therapeutic advances in acute PE …

Health risk stratification based on computed tomography pulmonary artery obstruction index for acute pulmonary embolism

F Guo, G Zhu, J Shen, Y Ma - Scientific Reports, 2018 - nature.com
Early effective identification of high-risk patients for acute pulmonary embolism (APE)
contributes to timely treatment. The pulmonary artery obstruction index (PAOI) in computed …

Technical efficiency, short-term clinical results and safety of a large-bore aspiration catheter in acute pulmonary embolism–A retrospective case study

JT Yasin, R Davis, A Saemi, H Regunath, A Krvavac… - Lung India, 2020 - journals.lww.com
Background: Mechanical thrombectomy plays an important role in the management of acute
pulmonary embolism (PE), either when rapid clot dissolution is needed or when …

Predictive value of mean platelet volume for pulmonary embolism recurrence

O Araz, FS Albez, EY Ucar, B Kerget, N Yılmaz… - Lung, 2017 - Springer
Purpose Recurrence is a major clinical problem in patients with pulmonary embolism and
can affect mortality. The decision to discontinue treatment is important for recurrence and is …

[HTML][HTML] Life expectancy in cancer patients with pulmonary thromboembolism: From clinical prognostic biomarkers and paraclinical investigations to therapeutic …

DM Nemtut, CA Petreanu… - Experimental …, 2024 - build.spandidos-publications.com
Pulmonary embolisms (PEs) are obstructions of the pulmonary arteries by thrombi, which
are emboli and they most frequently originate from the deep venous system of the inferior …

Epidemiological study about the mental state of patients after a pulmonary embolism or deep venous thrombosis event

S Kämpf, L Weißbach, R Zotz - Blood Coagulation & Fibrinolysis, 2022 - journals.lww.com
Venous thromboembolism (VTE) occurs frequently and represents a serious threat to patient
health. However, its effects on mental health have not been studied sufficiently. The …

Effect of simvastatin on the SIRT2/NF-κB pathway in rats with acute pulmonary embolism

ZY Wu, H Li, YJ Tang - Pharmaceutical biology, 2018 - Taylor & Francis
Context: Statins have been widely used in acute pulmonary embolism (APE), while
simvastatin has been well-established for the prevention of pulmonary hypertension, which …