[HTML][HTML] Ion Channels and Ionotropic Receptors in Astrocytes: Physiological Functions and Alterations in Alzheimer's Disease and Glioblastoma

A Lia, A Di Spiezio, L Vitalini, M Tore, G Puja, G Losi - Life, 2023 - mdpi.com
The human brain is composed of nearly one hundred billion neurons and an equal number
of glial cells, including macroglia, ie, astrocytes and oligodendrocytes, and microglia, the …

Roles of TRPM channels in glioma

Z Chen, H Xie, J Liu, JJ Zhao, R Huang… - Cancer Biology & …, 2024 - Taylor & Francis
Gliomas are the most common type of primary brain tumor. Despite advances in treatment, it
remains one of the most aggressive and deadly tumor of the central nervous system (CNS) …

[HTML][HTML] Insights into the mechanisms governing P01 scorpion toxin effect against U87 glioblastoma cells oncogenesis

S Mlayah-Bellalouna, D Aissaoui-Zid… - Frontiers in …, 2023 - frontiersin.org
The emerging concept of small conductance Ca2+-activated potassium channels (SKCa) as
pharmacological target for cancer treatment has significantly increased in recent years. In …

[HTML][HTML] Loss of the large conductance calcium-activated potassium channel causes an increase in mitochondrial reactive oxygen species in glioblastoma cells

B Kulawiak, M Żochowska, P Bednarczyk… - … -European Journal of …, 2023 - Springer
Mitochondrial potassium (mitoK) channels play an important role in cellular physiology.
These channels are expressed in healthy tissues and cancer cells. Activation of mitoK …

Effect of AQP4 and its palmitoylation on the permeability of exogenous reactive oxygen species: Insights from computational study

Y Cao, H Wei, S Jiang, T Lu, P Nie, C Yang… - International Journal of …, 2023 - Elsevier
Abstract Aquaporin 4 (AQP4) facilitates the transport of reactive oxygen species (ROS). Both
cancer cells and the ionizing radiation microenvironment can induce posttranslational …

[HTML][HTML] Intrinsic and Microenvironmental Drivers of Glioblastoma Invasion

E De Fazio, M Pittarello, A Gans, B Ghosh… - International Journal of …, 2024 - mdpi.com
Gliomas are diffusely infiltrating brain tumors whose prognosis is strongly influenced by their
extent of invasion into the surrounding brain tissue. While lower-grade gliomas present more …