[HTML][HTML] Mitochondrial impairment: A common motif in neuropsychiatric presentation? The link to the tryptophan–kynurenine metabolic system

M Tanaka, Á Szabó, E Spekker, H Polyák, F Tóth… - Cells, 2022 - mdpi.com
Nearly half a century has passed since the discovery of cytoplasmic inheritance of human
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …

[HTML][HTML] Losing DNA methylation at repetitive elements and breaking bad

XG Pappalardo, V Barra - Epigenetics & chromatin, 2021 - Springer
Background DNA methylation is an epigenetic chromatin mark that allows heterochromatin
formation and gene silencing. It has a fundamental role in preserving genome stability …

Toward trauma‐informed applications of behavior analysis

A Rajaraman, JL Austin, HC Gover… - Journal of Applied …, 2022 - Wiley Online Library
Despite a growing acknowledgement of the importance of understanding the impacts of
trauma on therapeutic approaches across human service disciplines, discussions of trauma …

Adverse childhood experiences in African Americans: Framework, practice, and policy.

JN Hampton-Anderson, S Carter, N Fani… - American …, 2021 - psycnet.apa.org
Adverse childhood experiences (ACEs) disproportionately impact African Americans
because of profound subjection to historical-systemic oppression in addition to personal and …

[HTML][HTML] Cell-type-specific epigenetic effects of early life stress on the brain

MF Rahman, PO McGowan - Translational Psychiatry, 2022 - nature.com
Early life stress (ELS) induces long-term phenotypic adaptations that contribute to increased
vulnerability to a host of neuropsychiatric disorders. Epigenetic mechanisms, including DNA …

[HTML][HTML] Epigenetics of childhood trauma: Long term sequelae and potential for treatment

KM Thumfart, A Jawaid, K Bright, M Flachsmann… - Neuroscience & …, 2022 - Elsevier
Childhood trauma (CT) can have persistent effects on the brain and is one of the major risk
factors for neuropsychiatric diseases in adulthood. Recent advances in the field of …

[HTML][HTML] The role of cytokines in the pathogenesis of schizophrenia

B Dawidowski, A Górniak, P Podwalski… - Journal of Clinical …, 2021 - mdpi.com
Schizophrenia is a chronic mental illness of unknown etiology. A growing and compelling
body of evidence implicates immunologic dysfunction as the key element in its …

[HTML][HTML] The influence of adverse childhood experiences in pain management: mechanisms, processes, and trauma-informed care

LV Tidmarsh, R Harrison, D Ravindran… - Frontiers in Pain …, 2022 - frontiersin.org
Adverse childhood experiences (ACEs) increase the likelihood of reduced physical and
psychological health in adulthood. Though understanding and psychological management …

The role of epigenetics in psychological resilience

D Smeeth, S Beck, EG Karam, M Pluess - The Lancet Psychiatry, 2021 - thelancet.com
There is substantial variation in people's responses to adversity, with a considerable
proportion of individuals displaying psychological resilience. Epigenetic mechanisms are …

[HTML][HTML] Glucocorticoid signaling and epigenetic alterations in stress-related disorders

N Mourtzi, A Sertedaki, E Charmandari - International Journal of …, 2021 - mdpi.com
Stress is defined as a state of threatened or perceived as threatened homeostasis. The well-
tuned coordination of the stress response system is necessary for an organism to respond to …