[HTML][HTML] Mitochondrial impairment: A common motif in neuropsychiatric presentation? The link to the tryptophan–kynurenine metabolic system
M Tanaka, Á Szabó, E Spekker, H Polyák, F Tóth… - Cells, 2022 - mdpi.com
Nearly half a century has passed since the discovery of cytoplasmic inheritance of human
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …
[HTML][HTML] Losing DNA methylation at repetitive elements and breaking bad
XG Pappalardo, V Barra - Epigenetics & chromatin, 2021 - Springer
Background DNA methylation is an epigenetic chromatin mark that allows heterochromatin
formation and gene silencing. It has a fundamental role in preserving genome stability …
formation and gene silencing. It has a fundamental role in preserving genome stability …
Toward trauma‐informed applications of behavior analysis
Despite a growing acknowledgement of the importance of understanding the impacts of
trauma on therapeutic approaches across human service disciplines, discussions of trauma …
trauma on therapeutic approaches across human service disciplines, discussions of trauma …
Adverse childhood experiences in African Americans: Framework, practice, and policy.
Adverse childhood experiences (ACEs) disproportionately impact African Americans
because of profound subjection to historical-systemic oppression in addition to personal and …
because of profound subjection to historical-systemic oppression in addition to personal and …
[HTML][HTML] Cell-type-specific epigenetic effects of early life stress on the brain
MF Rahman, PO McGowan - Translational Psychiatry, 2022 - nature.com
Early life stress (ELS) induces long-term phenotypic adaptations that contribute to increased
vulnerability to a host of neuropsychiatric disorders. Epigenetic mechanisms, including DNA …
vulnerability to a host of neuropsychiatric disorders. Epigenetic mechanisms, including DNA …
[HTML][HTML] Epigenetics of childhood trauma: Long term sequelae and potential for treatment
KM Thumfart, A Jawaid, K Bright, M Flachsmann… - Neuroscience & …, 2022 - Elsevier
Childhood trauma (CT) can have persistent effects on the brain and is one of the major risk
factors for neuropsychiatric diseases in adulthood. Recent advances in the field of …
factors for neuropsychiatric diseases in adulthood. Recent advances in the field of …
[HTML][HTML] The role of cytokines in the pathogenesis of schizophrenia
B Dawidowski, A Górniak, P Podwalski… - Journal of Clinical …, 2021 - mdpi.com
Schizophrenia is a chronic mental illness of unknown etiology. A growing and compelling
body of evidence implicates immunologic dysfunction as the key element in its …
body of evidence implicates immunologic dysfunction as the key element in its …
[HTML][HTML] The influence of adverse childhood experiences in pain management: mechanisms, processes, and trauma-informed care
LV Tidmarsh, R Harrison, D Ravindran… - Frontiers in Pain …, 2022 - frontiersin.org
Adverse childhood experiences (ACEs) increase the likelihood of reduced physical and
psychological health in adulthood. Though understanding and psychological management …
psychological health in adulthood. Though understanding and psychological management …
The role of epigenetics in psychological resilience
There is substantial variation in people's responses to adversity, with a considerable
proportion of individuals displaying psychological resilience. Epigenetic mechanisms are …
proportion of individuals displaying psychological resilience. Epigenetic mechanisms are …
[HTML][HTML] Glucocorticoid signaling and epigenetic alterations in stress-related disorders
Stress is defined as a state of threatened or perceived as threatened homeostasis. The well-
tuned coordination of the stress response system is necessary for an organism to respond to …
tuned coordination of the stress response system is necessary for an organism to respond to …