Lipid-based nanoparticles for delivery of vaccine adjuvants and antigens: toward multicomponent vaccines
D Chatzikleanthous, DT O'Hagan… - Molecular …, 2021 - ACS Publications
Despite the many advances that have occurred in the field of vaccine adjuvants, there are
still unmet needs that may enable the development of vaccines suitable for more …
still unmet needs that may enable the development of vaccines suitable for more …
Nano-traditional Chinese medicine: a promising strategy and its recent advances
D Wei, H Yang, Y Zhang, X Zhang, J Wang… - Journal of Materials …, 2022 - pubs.rsc.org
Traditional Chinese Medicine (TCM) has been applied to the prevention and treatment of
numerous diseases and has an irreplaceable role in rehabilitation and health care …
numerous diseases and has an irreplaceable role in rehabilitation and health care …
[HTML][HTML] Manufacturing considerations for the development of lipid nanoparticles using microfluidics
CB Roces, G Lou, N Jain, S Abraham, A Thomas… - Pharmaceutics, 2020 - mdpi.com
In the recent of years, the use of lipid nanoparticles (LNPs) for RNA delivery has gained
considerable attention, with a large number in the clinical pipeline as vaccine candidates or …
considerable attention, with a large number in the clinical pipeline as vaccine candidates or …
Microfluidic manufacturing of liposomes: development and optimization by design of experiment and machine learning
Liposomes constitute the most exploited drug-nanocarrier with several liposomal drugs on
the market. Microfluidic-based preparation methods stand up as a promising approach with …
the market. Microfluidic-based preparation methods stand up as a promising approach with …
[HTML][HTML] Microfluidic manufacture of lipid-based nanomedicines
K Osouli-Bostanabad, S Puliga, DR Serrano, A Bucchi… - Pharmaceutics, 2022 - mdpi.com
Nanoparticulate technologies have revolutionized drug delivery allowing for passive and
active targeting, altered biodistribution, controlled drug release (temporospatial or triggered) …
active targeting, altered biodistribution, controlled drug release (temporospatial or triggered) …
[HTML][HTML] Lipid-based drug delivery systems for diseases managements
DL Gbian, A Omri - Biomedicines, 2022 - mdpi.com
Liposomes are tiny lipid-based vesicles composed of one or more lipid bilayers, which
facilitate the encapsulation of hydrophilic, lipophilic, and amphiphilic biological active …
facilitate the encapsulation of hydrophilic, lipophilic, and amphiphilic biological active …
Consideration for the scale‐up manufacture of nanotherapeutics—A critical step for technology transfer
While nano‐enabled biotechnology is offering great promise, in certain areas providing
fundamental paradigm shift for disease management, we are rapidly moving into a new era …
fundamental paradigm shift for disease management, we are rapidly moving into a new era …
[HTML][HTML] Use of microfluidics to prepare lipid-based nanocarriers
A Vogelaar, S Marcotte, J Cheng, B Oluoch, J Zaro - Pharmaceutics, 2023 - mdpi.com
Lipid-based nanoparticles (LBNPs) are an important tool for the delivery of a diverse set of
drug cargoes, including small molecules, oligonucleotides, and proteins and peptides …
drug cargoes, including small molecules, oligonucleotides, and proteins and peptides …
Optimization of large-scale manufacturing of biopolymeric and lipid nanoparticles using microfluidic swirl mixers
MA Tomeh, MH Mansor, R Hadianamrei, W Sun… - International Journal of …, 2022 - Elsevier
Nanoparticles (NPs) have great potential as efficient drug delivery systems (DDSs) that have
been widely used in cancer therapy and vaccines especially in the past decade. The rise in …
been widely used in cancer therapy and vaccines especially in the past decade. The rise in …
[HTML][HTML] Lipid nanoparticle technology for delivering biologically active fatty acids and monoglycerides
There is enormous interest in utilizing biologically active fatty acids and monoglycerides to
treat phospholipid membrane-related medical diseases, especially with the global health …
treat phospholipid membrane-related medical diseases, especially with the global health …