Lipid-based nanoparticles for delivery of vaccine adjuvants and antigens: toward multicomponent vaccines

D Chatzikleanthous, DT O'Hagan… - Molecular …, 2021 - ACS Publications
Despite the many advances that have occurred in the field of vaccine adjuvants, there are
still unmet needs that may enable the development of vaccines suitable for more …

Nano-traditional Chinese medicine: a promising strategy and its recent advances

D Wei, H Yang, Y Zhang, X Zhang, J Wang… - Journal of Materials …, 2022 - pubs.rsc.org
Traditional Chinese Medicine (TCM) has been applied to the prevention and treatment of
numerous diseases and has an irreplaceable role in rehabilitation and health care …

[HTML][HTML] Manufacturing considerations for the development of lipid nanoparticles using microfluidics

CB Roces, G Lou, N Jain, S Abraham, A Thomas… - Pharmaceutics, 2020 - mdpi.com
In the recent of years, the use of lipid nanoparticles (LNPs) for RNA delivery has gained
considerable attention, with a large number in the clinical pipeline as vaccine candidates or …

Microfluidic manufacturing of liposomes: development and optimization by design of experiment and machine learning

R Rebollo, F Oyoun, Y Corvis… - … Applied Materials & …, 2022 - ACS Publications
Liposomes constitute the most exploited drug-nanocarrier with several liposomal drugs on
the market. Microfluidic-based preparation methods stand up as a promising approach with …

[HTML][HTML] Microfluidic manufacture of lipid-based nanomedicines

K Osouli-Bostanabad, S Puliga, DR Serrano, A Bucchi… - Pharmaceutics, 2022 - mdpi.com
Nanoparticulate technologies have revolutionized drug delivery allowing for passive and
active targeting, altered biodistribution, controlled drug release (temporospatial or triggered) …

[HTML][HTML] Lipid-based drug delivery systems for diseases managements

DL Gbian, A Omri - Biomedicines, 2022 - mdpi.com
Liposomes are tiny lipid-based vesicles composed of one or more lipid bilayers, which
facilitate the encapsulation of hydrophilic, lipophilic, and amphiphilic biological active …

Consideration for the scale‐up manufacture of nanotherapeutics—A critical step for technology transfer

X Liu, H Meng - View, 2021 - Wiley Online Library
While nano‐enabled biotechnology is offering great promise, in certain areas providing
fundamental paradigm shift for disease management, we are rapidly moving into a new era …

[HTML][HTML] Use of microfluidics to prepare lipid-based nanocarriers

A Vogelaar, S Marcotte, J Cheng, B Oluoch, J Zaro - Pharmaceutics, 2023 - mdpi.com
Lipid-based nanoparticles (LBNPs) are an important tool for the delivery of a diverse set of
drug cargoes, including small molecules, oligonucleotides, and proteins and peptides …

Optimization of large-scale manufacturing of biopolymeric and lipid nanoparticles using microfluidic swirl mixers

MA Tomeh, MH Mansor, R Hadianamrei, W Sun… - International Journal of …, 2022 - Elsevier
Nanoparticles (NPs) have great potential as efficient drug delivery systems (DDSs) that have
been widely used in cancer therapy and vaccines especially in the past decade. The rise in …

[HTML][HTML] Lipid nanoparticle technology for delivering biologically active fatty acids and monoglycerides

JYB Tan, BK Yoon, NJ Cho, J Lovrić, M Jug… - International journal of …, 2021 - mdpi.com
There is enormous interest in utilizing biologically active fatty acids and monoglycerides to
treat phospholipid membrane-related medical diseases, especially with the global health …