Background Mutations in the gene encoding thymidine kinase 2 (TK2) result in the
myopathic form of mitochondrial DNA depletion syndrome which is a mitochondrial …

High-yielding cereals and other staples have produced adequate calories to ward off
starvation for much of the world over several decades. However, deficiencies in certain …

l-Asparaginase (EC 3.5. 1.1) was first used as a component of combination drug therapies to
treat acute lymphoblastic leukemia (ALL), a cancer of the blood and bone marrow, almost 50 …

Insulin resistance (IR) is a key pathological feature of metabolic syndrome and subsequently
causes serious health problems with an increased risk of several common metabolic …

Nutrition exerts a life-long impact on human health, and the interaction between nutrition
and health has been known for centuries. The recent literature has suggested that nutrition …

In this study, we chose a carnivorous fish, turbot (Scophthalmus maximus L.), to examine its
nutrient-sensing and metabolic responses after ingestion of diets with fishmeal (FM), or 45 …

In most mammalian cells, insulin and glucocorticoids promote anabolism and catabolism,
respectively. Whereas the opposing effects of insulin and glucocorticoids on catabolic gene …

Background: Fish cannot use carbohydrate efficiently and instead utilize protein for energy
supply, thus limiting dietary protein storage. Protein deposition is dependent on protein …

Rationale: Aldehyde accumulation is regarded as a pathognomonic feature of oxidative
stress–associated cardiovascular disease. Objective: We investigated how the heart …

The objective of this study was to evaluate the effect of dietary protein quality on intestinal
peptide transporter (PepT1), amino acid transporter [Na+-independent cationic and …