Hypoxia, low oxygen (O2) level, is a hallmark of solid cancers, especially hepatocellular
carcinoma (HCC), one of the most common and fatal cancers worldwide. Hypoxia …

The Warburg effect, one of the hallmarks of tumors, produces large amounts of lactate and
generates an acidic tumor microenvironment via using glucose for glycolysis. As a …

Hepatocellular carcinoma (HCC) metabolism is redirected to glycolysis to enhance the
production of metabolic compounds employed by cancer cells to produce proteins, lipids …

Abstract Background Lactate dehydrogenase A (LDHA) is overexpressed and associated
with poor prognosis in many kinds of cancer. In the current study, we evaluated the …

MYC is a notorious oncogene in a vast network of malignancies, whereas liver‐specific
microRNA‐(miR‐) 122‐5p is downregulated in hepatocellular cancer (HCC). Here, we …

Abstract Background and Aims Hepatocellular carcinoma (HCC) is a multistep process
whereby abnormally proliferating cancer cells undergo extensive metabolic reprogramming …

Radiotherapy is widely used as an indispensable treatment option for cervical cancer
patients. However, radioresistance always occurs and has become a big obstacle to …

Recent pharmacological research on milk whey, a byproduct of the dairy industry, has
identified several therapeutic properties that could be exploited in modern medicine. In the …

Metastasis is the major reason for poor prognosis and high fatality in hepatocellular
carcinoma (HCC). Due to the “Warburg effect”, an acidic tumor microenvironment (TME) …

Hepatocellular carcinoma (HCC) is a tumor that exhibits glucometabolic reprogramming,
with a high incidence and poor prognosis. Usually, HCC is not discovered until an advanced …