Acetaminophen (APAP) overdose is the leading cause of drug-induced acute liver failure in
many developed countries. Mitochondrial oxidative stress is considered to be the …

Tea is particularly rich in polyphenols, including catechins and theaflavins, thearubigins,
flavonols, and phenolic acids, which are believed to contribute to the health benefits of tea …

The current understanding of the complex role of ROS in the organism and pathological
sequelae of oxidative stress points to the necessity of comprehensive studies of antioxidant …

Oxidative stress plays a key role in the pathogenesis of various diseases. Antioxidants
protect the cells and tissues from oxidative stress by scavenging free radicals and reactive …

There is a significant need to evaluate the therapeutic potential of natural products and other
compounds purported to be hepatoprotective. Acetaminophen-induced liver injury …

Andrographis paniculata (Family: Acanthaceae) and Swertia chirayita (Family:
Gentianaceae) are two controversial medicinal plants used as Kiriyattu, having similar …

Extracts from medicinal plants, many of which have been used for centuries, are increasingly
tested in models of hepatotoxicity. One of the most popular models to evaluate the …

Acute exposure of acetaminophen (APAP), a widely used analgesic and antipyretic drug,
causes severe renal damage and no specific agent has been reported so far that plays any …

Background The liver plays an important role in regulating the metabolic processes and is
the most frequently targeted organ by toxic chemicals. Acetaminophen (APAP) is a well …

Jasminum grandiflorum L.(JG) is a medicinal plant containing many bioactive ingredients.
Herein, we analyzed the effects of four different extracts and two compounds of JG on acute …