γδ T cells: origin and fate, subsets, diseases and immunotherapy
Y Hu, Q Hu, Y Li, L Lu, Z Xiang, Z Yin… - … and Targeted Therapy, 2023 - nature.com
The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …
hyperactivation, highlights the potential of immune renormalization as a promising strategy …
Data analysis guidelines for single-cell RNA-seq in biomedical studies and clinical applications
M Su, T Pan, QZ Chen, WW Zhou, Y Gong, G Xu… - Military Medical …, 2022 - Springer
The application of single-cell RNA sequencing (scRNA-seq) in biomedical research has
advanced our understanding of the pathogenesis of disease and provided valuable insights …
advanced our understanding of the pathogenesis of disease and provided valuable insights …
A single-cell atlas of the peripheral immune response in patients with severe COVID-19
There is an urgent need to better understand the pathophysiology of Coronavirus disease
2019 (COVID-19), the global pandemic caused by SARS-CoV-2, which has infected more …
2019 (COVID-19), the global pandemic caused by SARS-CoV-2, which has infected more …
The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination
Emerging evidence indicates a fundamental role for the epigenome in immunity. Here, we
mapped the epigenomic and transcriptional landscape of immunity to influenza vaccination …
mapped the epigenomic and transcriptional landscape of immunity to influenza vaccination …
Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19
Our understanding of protective versus pathological immune responses to SARS-CoV-2, the
virus that causes coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of …
virus that causes coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of …
Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19
A better understanding of the metabolic alterations in immune cells during severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may elucidate the wide diversity …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may elucidate the wide diversity …
SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
There is pressing urgency to understand the pathogenesis of the severe acute respiratory
syndrome coronavirus clade 2 (SARS-CoV-2), which causes the disease COVID-19. SARS …
syndrome coronavirus clade 2 (SARS-CoV-2), which causes the disease COVID-19. SARS …
Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones
Understanding the drivers and markers of clonally expanding HIV-1-infected CD4+ T cells is
essential for HIV-1 eradication. We used single-cell ECCITE-seq, which captures surface …
essential for HIV-1 eradication. We used single-cell ECCITE-seq, which captures surface …
Towards a comprehensive evaluation of dimension reduction methods for transcriptomic data visualization
Dimension reduction (DR) algorithms project data from high dimensions to lower
dimensions to enable visualization of interesting high-dimensional structure. DR algorithms …
dimensions to enable visualization of interesting high-dimensional structure. DR algorithms …
Combined protein and nucleic acid imaging reveals virus-dependent B cell and macrophage immunosuppression of tissue microenvironments
Understanding the mechanisms of HIV tissue persistence necessitates the ability to visualize
tissue microenvironments where infected cells reside; however, technological barriers limit …
tissue microenvironments where infected cells reside; however, technological barriers limit …