[HTML][HTML] Neuroinflammation in cerebral ischemia and ischemia/reperfusion injuries: from pathophysiology to therapeutic strategies

A Jurcau, A Simion - International journal of molecular sciences, 2021 - mdpi.com
Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

Systemic inflammation after stroke: implications for post‐stroke comorbidities

A Simats, A Liesz - EMBO molecular medicine, 2022 - embopress.org
Immunological mechanisms have come into the focus of current translational stroke
research, and the modulation of neuroinflammatory pathways has been identified as a …

Ischaemic stroke

BCV Campbell, DA De Silva, MR Macleod… - Nature reviews Disease …, 2019 - nature.com
Stroke is the second highest cause of death globally and a leading cause of disability, with
an increasing incidence in developing countries. Ischaemic stroke caused by arterial …

[HTML][HTML] Nrf2 regulates oxidative stress and its role in cerebral ischemic stroke

L Wang, X Zhang, X Xiong, H Zhu, R Chen, S Zhang… - Antioxidants, 2022 - mdpi.com
Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain,
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …

[HTML][HTML] The association of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and lymphocyte to monocyte ratio with post-thrombolysis early neurological …

P Gong, Y Liu, Y Gong, G Chen, X Zhang… - Journal of …, 2021 - Springer
Background and purpose To investigate the association of neutrophil to lymphocyte ratio
(NLR), platelet to lymphocyte ratio (PLR), and lymphocyte to monocyte ratio (LMR) with post …

[HTML][HTML] Interaction of microglia and astrocytes in the neurovascular unit

L Liu, J Liu, J Bao, Q Bai, G Wang - Frontiers in immunology, 2020 - frontiersin.org
The interaction between microglia and astrocytes significantly influences neuroinflammation.
Microglia/astrocytes, part of the neurovascular unit (NVU), are activated by various brain …

Targeting ferroptosis: pathological mechanism and treatment of ischemia‐reperfusion injury

X Li, N Ma, J Xu, Y Zhang, P Yang, X Su… - Oxidative Medicine …, 2021 - Wiley Online Library
Ischemia‐reperfusion (I/R) is a pathological process that occurs in many organs and
diseases. Reperfusion, recovery of blood flow, and reoxygenation often lead to reperfusion …

Action plan for stroke in Europe 2018–2030

B Norrving, J Barrick, A Davalos… - European stroke …, 2018 - journals.sagepub.com
Two previous pan-European consensus meetings, the 1995 and 2006 Helsingborg
meetings, were convened to review the scientific evidence and the state of current services …

The predictive role of systemic inflammation response index (SIRI) in the prognosis of stroke patients

Y Zhang, Z Xing, K Zhou, S Jiang - Clinical interventions in aging, 2021 - Taylor & Francis
Purpose Stroke is a disease associated with high mortality. Many inflammatory indicators
such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte …

Encouraging an excitable brain state: mechanisms of brain repair in stroke

MT Joy, ST Carmichael - Nature Reviews Neuroscience, 2021 - nature.com
Stroke induces a plastic state in the brain. This period of enhanced plasticity leads to the
sprouting of new axons, the formation of new synapses and the remapping of sensory-motor …