Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006

GG Zhanel, M DeCorby, N Laing… - Antimicrobial agents …, 2008 - Am Soc Microbiol
ABSTRACT Between 1 September 2005 and 30 June 2006, 19 medical centers collected
4,180 isolates recovered from clinical specimens from patients in intensive care units (ICUs) …

[HTML][HTML] Appearance of β-lactam Resistance Genes in Agricultural Soils and Clinical Isolates over the 20th Century

DW Graham, CW Knapp, BT Christensen… - Scientific reports, 2016 - nature.com
Debate exists about whether agricultural versus medical antibiotic use drives increasing
antibiotic resistance (AR) across nature. Both sectors have been inconsistent at antibiotic …

Escherichia coli ST131: the quintessential example of an international multiresistant high-risk clone

AJ Mathers, G Peirano, JDD Pitout - Advances in applied microbiology, 2015 - Elsevier
Escherichia coli ST131emerged during the early to mid-2000s is an important human
pathogen, has spread extensively throughout the world, and is responsible for the rapid …

Evaluation of Screening Methods To Detect Plasmid-Mediated AmpC in Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis

TY Tan, LSY Ng, J He, TH Koh… - Antimicrobial agents and …, 2009 - Am Soc Microbiol
There are currently no standardized phenotypic methods for the screening and detection of
AmpC enzymes. This study aimed to evaluate different methods to detect AmpC enzymes in …

Increased Waterborne blaNDM-1 Resistance Gene Abundances Associated with Seasonal Human Pilgrimages to the Upper Ganges River

ZS Ahammad, TR Sreekrishnan… - … science & technology, 2014 - ACS Publications
Antibiotic resistance (AR) is often rooted in inappropriate antibiotic use, but poor water
quality and inadequate sanitation exacerbate the problem, especially in emerging countries …

Detection of AmpC beta-lactamase in Escherichia coli: comparison of three phenotypic confirmation assays and genetic analysis

S Peter-Getzlaff, S Polsfuss, M Poledica… - Journal of clinical …, 2011 - Am Soc Microbiol
Two mechanisms account for AmpC activity in Escherichia coli, namely, mutations in the
ampC promoter and attenuator regions resulting in ampC overexpression and acquisition of …

[HTML][HTML] Risk factors for colonization with extended-spectrum β-lactamase–producing bacteria and intensive care unit admission

AD Harris, JC McGregor, JA Johnson… - Emerging infectious …, 2007 - ncbi.nlm.nih.gov
Extended-spectrum β-lactamase (ESBL)–producing bacteria are emerging pathogens. To
analyze risk factors for colonization with ESBL-producing bacteria at intensive care unit …

Screening for extended-spectrum β-lactamase-producing Enterobacteriaceae among high-risk patients and rates of subsequent bacteremia

P Reddy, M Malczynski, A Obias… - Clinical infectious …, 2007 - academic.oup.com
Background. Bloodstream infections due to extended-spectrum β-lactamase (ESBL)–
producing Enterobacteriaceae have been associated with increased hospital costs, length of …

Secular trends in gram-negative resistance among urinary tract infection hospitalizations in the United States, 2000–2009

MD Zilberberg, AF Shorr - Infection Control & Hospital Epidemiology, 2013 - cambridge.org
Objective. Urinary tract infections (UTIs) are common among hospitalized patients. Selection
of an appropriate antibiotic for this infection requires knowledge of both its general …

Extended‐spectrum β‐lactamases in North America, 1987–2006

K Bush - Clinical Microbiology and Infection, 2008 - Wiley Online Library
Extended‐spectrum β‐lactamases (ESBLs) derived from the TEM‐1 β‐lactamase were first
identified in the USA in outbreak strains of Klebsiella pneumoniae in the middle to late …