The incidence of beta-lactam resistance among clinical isolates is a major health concern. A
key method to study the emergence of antibiotic resistance is adaptive laboratory evolution …

The epidemiology of clavulanic acid-inhibited extended-spectrum β-lactamases (ESBLs)
was investigated among infection-associated enterobacterial isolates at the University …

Carbapenems are considered the last-resort antibiotics to treat infections caused by
multidrug-resistant Gram-negative bacilli. The Klebsiella pneumoniae carbapenemase …

This study was designed to characterise 30 non-duplicate extended-spectrum β-lactamase
(ESBL)-producing Escherichia coli clinical isolates from the community in the Chicago …

Background: AmpC β-lactamases are often plasmid mediated that hydrolyze all b-lactam
antibiotics except cefepime and carbapenems. Aim of the study: We aimed to evaluate the …

Introduction. Antibiotic resistant mutants producing extendedspectrum beta-lactamase
(ESBL) have emerged among Escherichia coli AND KLEBSIELLA PNEUMONIAE. This study …

Citrobacter spp. are opportunistic human pathogens which can cause nosocomial infections,
sporadic infections and outbreaks. In order to determine the genetic diversity, in vitro …

Purpose. Resistant Gram-negative bacterial (GNB) infections, apart from tremendously
escalating the cost of treatment, are a cause for substantial morbidity and mortality among …

Horizontal gene transfer may occur between distantly related bacteria, thus leading to
genetic plasticity and in some cases to acquisition of novel resistance traits. Proteus …

Introduction: Few reports about the prevalence and genetic basis of extended spectrum beta-
lactamases (ESBLs) are available from Saudi Arabia. We sought to determine the …