Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …

Due to rising incidence rates of liver cancer and worries about the toxicity of current
chemotherapeutic medicines, the hunt for further alternative methods to treat this malignancy …

Hepatocellular carcinoma (HCC) is considered one of the greatest challenges to human life
and is the most common form of liver cancer. Treatment of HCC depends on chemotherapy …

High mobility group A 2 (HMGA2) is a protein that modulates the structure of chromatin in the
nucleus. Importantly, aberrant expression of HMGA2 occurs during carcinogenesis, and this …

Tripartite motif (TRIM) family is assigned to RING-finger-containing ligases harboring the
largest number of proteins in E3 ubiquitin ligating enzymes. E3 ubiquitin ligases target the …

Background Malignant transformation from hepatic fibrosis to carcinogenesis may be a
therapeutic target for hepatocellular carcinoma (HCC). The aim of this study was to evaluate …

Schizandrin B (SchB) protects against oxidative, inflammatory, and ferroptotic injury.
Oxidative stress and inflammation are indispensably involved in nephrolithiasis and …

Osteosarcoma (OS) is a malignant bone carcinoma that affects people in childhood and
adulthood. The heterogeneous nature and chromosomal instability represent certain …

Background Infertility is one of the major factors affecting most people around the world.
Short-term exposure to high temperatures can cause hyperthermia, which is one of the …

Evidence recently showed that pleiotropic cytokine interferon-gamma (IFN-γ) in the tumor
microenvironment (TME) plays a positive role in hepatocellular carcinoma (HCC) …