Gastroesophageal reflux disease (GERD) is the most prevalent gastrointestinal disorder in
the United States, and leads to substantial morbidity, though associated mortality is rare. The …

Helicobacter pylori is the leading cause of peptic ulcer disease. The infection has been
implicated in more than 75% of duodenal ulcer cases and 17% of gastric ulcer cases. H …

Pathogenic potentials of the gastric pathogen, Helicobacter pylori, have been proposed,
evaluated, and confirmed by many laboratories for nearly 4 decades since its serendipitous …

Helicobacter pylori Infection is formally recognised as an infectious disease, an entity that is
now included in the International Classification of Diseases 11th Revision. This in principle …

Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Novel culture-independent techniques have recently demonstrated that the lower respiratory
tract, historically considered sterile in health, contains diverse communities of microbes: the …

Although gastric adenocarcinoma is associated with the presence of Helicobacter pylori in
the stomach, only a small fraction of colonized individuals develop this common malignancy …

The association between chronic inflammation and cancer is now well established. This
association has recently received renewed interest with the recognition that microbial …

Humans have been colonized by Helicobacter pylori for at least 50,000 years and probably
throughout their evolution. H. pylori has adapted to humans, colonizing children and …

We performed a detailed analysis of the epidemiology of gastric carcinoma, based upon a
review of the literature in English. The analysis reveals many puzzling features. There has …