Endometriosis is histologically characterized by the displacement of endometrial tissue to
extrauterine locations including the pelvic peritoneum, ovaries, and bowel. An important …

Urine has become one of the most attractive biofluids in clinical proteomics as it can be
obtained non-invasively in large quantities and is stable compared with other biofluids. The …

Urine is a readily and noninvasively obtainable body fluid. Mass spectrometry (MS)-based
proteomics has shown that urine contains thousands of proteins. Urine is a potential source …

Alzheimer′ s disease (AD) is the most common form of dementia that affects several million
people worldwide. The major neuropathological hallmarks of AD are the presence of …

A limitation of proteomic methods with respect to their clinical applicability is the lack of
possibilities to directly deduce the amount of a protein or peptide from a particular mass …

Diabetes mellitus is one of the most challenging health concerns of the 21st century. With at
least 30% of the diabetic population remaining undiagnosed, effective and early diagnosis is …

Proteome analysis has emerged as a powerful technology to decipher biological processes.
One of the main goals is to discover biomarkers for diseases from tissues and body fluids …

Background: Urine is a useful source of protein for biomarker discovery and assessment
because it is readily available, can be obtained by noninvasive collection methods, and …

A urine sample preparation workflow for the iTRAQ (isobaric tag for relative and absolute
quantitation) technique was established. The reproducibility of this platform was evaluated …

Exosomal nanoparticles (exosomes or nanovesicles) are biogenic membrane vesicles
secreted by various cell types and represent a conservative mechanism of intercellular and …