Cadmium (Cd) induced neurotoxicity has become a growing concern due to its potential
adverse effects on the Central Nervous System. Cd is a Heavy Metal (HM) that is released …

Shenfu injection (SFI), composed of ginseng and aconite, is a Chinese patent developed
from the classic traditional prescription Shenfu Decoction created more than 700 years ago …

Objective Myocardial infarction (MI) is linked to an imbalance in the supply and demand of
blood oxygen in the heart muscles. Beta-blockers and calcium antagonists are just two of the …

Plukenetia volubilis Linneo or Sacha Inchi (SI), a traditional natural remedy indigenous to
Peru and Brazil, has garnered global attention due to its exceptional nutritional composition …

Background Regulation of balance between vasoconstriction and vasodilation has become
a therapeutic target to vascular complications. However, Aluminium chloride, a naturally …

Marinobufagenin (MBG) is implicated in chronic kidney disease, where it removes Fli1-
induced inhibition of the collagen-1. We hypothesized that (i) in nephrectomized rats, aortic …

Valproic acid is an antiepileptic drug associated with skin-related issues like excessive hair
growth, hair loss, and skin rashes. In contrast, Moringa oleifera, rich in nutrients and …

Thiazolidinediones (TZDs)(eg pioglitazone and rosiglitazone), known insulin sensitiser
agents for type II diabetes mellitus, exhibit controversial effects on cardiac tissue. Despite …

Caffeine and theophylline use can lead to methylxanthine toxicity, resulting in life-
threatening tachyarrhythmias and hypotension. Esmolol, a beta-adrenergic antagonist, is a …

Methods Male Wistar rats were treated with IGF-1 (50 µg/kg), and 24 h after injection hearts
were excised. The level of interaction between Beclin-1 and the α 1 subunit of …