Background This is the fourth updated Enhanced Recovery After Surgery (ERAS®) Society
guideline presenting a consensus for optimal perioperative care in colorectal surgery and …

Sepsis is a dysregulated immune response to an infection that leads to organ dysfunction.
Knowledge of the pathophysiology of organ failure in sepsis is crucial for optimizing the …

Perioperative organ injury is among the leading causes of morbidity and mortality of surgical
patients. Among different types of perioperative organ injury, acute kidney injury occurs …

Background Acute kidney injury (AKI) in the intensive care unit is associated with significant
mortality and morbidity. Objectives To determine and update previous recommendations for …

Purpose We performed a systematic review and meta-analysis of studies investigating the
passive leg raising (PLR)-induced changes in cardiac output (CO) and in arterial pulse …

Sepsis is considered a major public health problem. Despite mortality being associated
consistently with organ compromise, the mechanisms by which sepsis causes multiple …

An understanding of the pathologic mechanisms of sepsis-induced AKI emphasizes the
important role of maladaptive responses to the septic insult. Preventive and therapeutic …

Aggressive fluid resuscitation to achieve a central venous pressure (CVP) greater than 8 mm
Hg has been promoted as the standard of care, in the management of patients with severe …

Objective: Evaluate the dose-response relationship between intraoperative fluid
administration and postoperative outcomes in a large cohort of surgical patients …

Acute kidney injury (AKI) is a multifaceted syndrome that occurs in different settings. The
course of AKI can be variable, from single hit and complete recovery, to multiple hits …