[HTML][HTML] Nanocarrier-based drug combination therapy for glioblastoma
M Zhao, D van Straten, MLD Broekman, V Préat… - Theranostics, 2020 - ncbi.nlm.nih.gov
The current achievements in treating glioblastoma (GBM) patients are not sufficient because
many challenges exist, such as tumor heterogeneity, the blood brain barrier, glioma stem …
many challenges exist, such as tumor heterogeneity, the blood brain barrier, glioma stem …
Mouse models of glioblastoma for the evaluation of novel therapeutic strategies
Glioblastoma (GBM) is an incurable brain tumor with a median survival of approximately 15
months despite an aggressive standard of care that includes surgery, chemotherapy, and …
months despite an aggressive standard of care that includes surgery, chemotherapy, and …
Tumor associated macrophages, as the dominant immune cells, are an indispensable target for immunologically cold tumor—glioma therapy?
N Tong, Z He, Y Ma, Z Wang, Z Huang… - Frontiers in cell and …, 2021 - frontiersin.org
Tumor microenvironment (TME) is the cornerstone of the occurrence, development, invasion
and diffusion of the malignant central nerve system (CNS) tumor, glioma. As the largest …
and diffusion of the malignant central nerve system (CNS) tumor, glioma. As the largest …
Impact of age and gender on glioblastoma onset, progression, and management
A Colopi, S Fuda, S Santi, A Onorato, V Cesarini… - Mechanisms of ageing …, 2023 - Elsevier
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults, while its
frequency in pediatric patients is 10–15%. For this reason, age is considered one of the …
frequency in pediatric patients is 10–15%. For this reason, age is considered one of the …
Ferroptosis: a new road towards cancer management
Ferroptosis is a recently described programmed cell death mechanism that is characterized
by the buildup of iron (Fe)-dependent lipid peroxides in cells and is morphologically …
by the buildup of iron (Fe)-dependent lipid peroxides in cells and is morphologically …
Dual and multi-targeted nanoparticles for site-specific brain drug delivery
Y Luo, H Yang, YF Zhou, B Hu - Journal of Controlled Release, 2020 - Elsevier
In recent years, nanomedicines have emerged as a promising method for central nervous
system drug delivery, enabling the drugs to overcome the blood-brain barrier and …
system drug delivery, enabling the drugs to overcome the blood-brain barrier and …
Single-cell transcriptomics revealed subtype-specific tumor immune microenvironments in human glioblastomas
Human glioblastoma (GBM), the most aggressive brain tumor, comprises six major subtypes
of malignant cells, giving rise to both inter-patient and intra-tumor heterogeneity. The …
of malignant cells, giving rise to both inter-patient and intra-tumor heterogeneity. The …
Extracellular vesicles in the glioblastoma microenvironment: a diagnostic and therapeutic perspective
Glioblastoma (GBM), is the most malignant form of gliomas and the most common and lethal
primary brain tumor in adults. Conventional cancer treatments have limited to no efficacy on …
primary brain tumor in adults. Conventional cancer treatments have limited to no efficacy on …
Exploring ncRNA-mediated regulation of EGFR signalling in glioblastoma: From mechanisms to therapeutics
Glioblastoma (GBM) is the most prevalent and deadly primary brain tumor type, with a
discouragingly low survival rate and few effective treatments. An important function of the …
discouragingly low survival rate and few effective treatments. An important function of the …
Liquid biopsy in glioblastoma
L Ronvaux, M Riva, A Coosemans, M Herzog… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma is the most common and malignant primary brain tumor.
Despite intensive research for new treatments, the survival of patients has not significantly …
Despite intensive research for new treatments, the survival of patients has not significantly …