Long-term follow-up of persisting mixed chimerism after partially T cell-depleted allogeneic stem cell transplantation

N Schaap, A Schattenberg, E Mensink, F Preijers… - Leukemia, 2002 - nature.com
Using red cell phenotyping (RCP) and/or cytogenetics (CYT) we identified 19 patients with
persisting mixed chimerism (MC) among 231 patients transplanted with partially T cell …

Enrichment of cell subpopulations applying automated MACS technique: purity, recovery and applicability for PCR-based chimerism analysis

A Willasch, S Eing, G Weber, S Kuci… - Bone marrow …, 2010 - nature.com
Enrichment of cell subpopulations is a prerequisite for lineage-specific chimerism analysis
(LCA), a frequent approach in follow-up after allo-SCT. An efficient enrichment technique is …

Feasibility study of preemptive withdrawal of immunosuppression based on chimerism testing in children undergoing myeloablative allogeneic transplantation for …

B Horn, S Soni, S Khan, A Petrovic, N Breslin… - Bone marrow …, 2009 - nature.com
An increasing percentage of autologous cells (increasing chimerism) in the whole blood
(WB) chimerism test following allogeneic transplant is related to a very high risk of relapse …

Serial quantification of lymphoid and myeloid mixed chimerism using multiplex PCR amplification of short tandem repeat-markers predicts graft rejection and relapse …

F Fernandez-Aviles, A Urbano-Ispizua, M Aymerich… - Leukemia, 2003 - nature.com
We used multiplex amplification of nine microsatellite sequences (PCR-STR) to analyse
chimerism in pure populations of T cells and neutrophils from peripheral blood from 40 …

Crucial role of timing of donor lymphocyte infusion in generating dissociated graft-versus-host and graft-versus-leukemia responses in mice receiving allogeneic bone …

AD Billiau, S Fevery, O Rutgeerts… - Blood, The Journal …, 2002 - ashpublications.org
A murine model of minor histocompatibility antigen-mismatched bone marrow
transplantation (BMT) was used to study the role of timing of donor lymphocyte infusion (DLI) …

WT1 gene expression: useful marker for minimal residual disease in childhood myelodysplastic syndromes and juvenile myelo‐monocytic leukemia?

P Bader, C Niemeyer, G Weber, T Coliva… - European journal of …, 2004 - Wiley Online Library
The WT1 gene is considered to be highly expressed in patients with acute myeloid leukemia
(AML), acute lymphoblastic leukemia and chronic myeloid leukemia and is thought to play a …

Characterization of cytotoxic function of CMV-pp65-specific CD8+ T-lymphocytes identified by HLA tetramers in recipients and donors of stem-cell transplants

SF Lacey, G Gallez-Hawkins, M Crooks… - …, 2002 - journals.lww.com
Background. Human cytomegalovirus (CMV) is a ubiquitous herpesvirus that is an important
complication of bone marrow and allogeneic stem-cell transplant (HSCT). CD8+ T …

Children with myelodysplastic syndrome (MDS) and increasing mixed chimaerism after allogeneic stem cell transplantation have a poor outcome which can be …

P Bader, C Niemeyer, A Willasch… - British journal of …, 2005 - Wiley Online Library
We recently reported that virtually all children with acute leukaemia and myelodysplastic
syndrome (MDS) who develop the phenotype of increasing mixed chimaerism (MC) after …

Quantitative analysis of chimerism after allogeneic stem cell transplantation by PCR amplification of microsatellite markers and capillary electrophoresis with …

C Acquaviva, M Duval, D Mirebeau, R Bertin, H Cave - Leukemia, 2003 - nature.com
Monitoring of engraftment by assessing chimerism is currently performed after allogeneic
bone marrow transplantation (BMT). Two main approaches are generally used for this …

[HTML][HTML] Evaluation and automation of hematopoietic chimerism analysis based on real-time quantitative polymerase chain reaction

TN Masmas, HO Madsen, SL Petersen… - Biology of Blood and …, 2005 - Elsevier
Chimerism analysis is an essential tool in the follow-up of patients after allogeneic stem cell
transplantation. High-resolution methods for chimerism analysis based on real-time …