Recently, a rising interest is given to neuroimmune communication in physiological and
neuropathological conditions. Meningeal immunity is a complex immune environment …

The classical liver-derived and serum-effective complement system is well appreciated as a
key mediator of host protection via instruction of innate and adaptive immunity. However …

In recent decades there has been a large focus on understanding the mechanisms of
peripheral immune cell infiltration into the central nervous system (CNS) in …

T cells expressing anti-CD19 chimeric antigen receptors (CARs) demonstrate impressive
efficacy in the treatment of systemic B cell malignancies, including B cell lymphoma …

The blood–brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB) represent
two complex structures protecting the central nervous system (CNS) against potentially …

Medulloblastoma is the most frequent malignant childhood brain tumor with a high morbidity.
Identification of new therapeutic targets would be instrumental in improving patient …

Myeloid-derived suppressor cells (MDSC) represent a heterogeneous population of
immature myeloid cells. Under normal conditions, they differentiate into macrophages …

Neuro-immune interactions are not only vital for the control of neurotropic pathogens, but
also appear to influence brain development and homeostasis. During immune surveillance …

The glymphatic system and meningeal lymphatics have recently been characterized.
Glymphatic system is a glia-dependent system of perivascular channels, and it plays an …

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS)
known for the manifestation of demyelinated lesions throughout the CNS, leading to …