Objective Pathogenesis of antiphospholipid syndrome (APS) isn't fully elucidated. We aimed
to identify gene signatures characterizing thrombotic primary APS (thrPAPS) and subgroups …

Antiphospholipid syndrome (APS) is a complex thrombo-inflammatory autoimmune disease
characterized by the presence of antiphospholipid antibodies (aPL). Women with APS are at …

IFNβ is a single-copy gene without an intron. Under normal circumstances, it shows low or
no expression in cells. It is upregulated only when the body needs it or is stimulated. Stimuli …

Иммуновоспалительные (аутоиммунные и аутовоспалительные) ревматические
заболевания-не только весьма распространенные и тяжелые хронические …

Antiphospholipid syndrome (APS) is characterized by thrombus formation, poor pregnancy
outcomes, and a proinflammatory response. H3K4me3‐related monocytes activation are key …

Systemic lupus erythematosus (SLE) is an autoimmune disease with multi-system
involvement as the main manifestation, and has complex and diverse clinical features …

Background Alterations of the trimethylation of histone 3 lysine 4 (H3K4me3) mark in
monocytes are implicated in the development of autoimmune diseases. Therefore, the …

Aim of the work To describe the clinical and laboratory characteristics of patients with
primary and secondary antiphospholipid syndrome (APS) in an Egyptian cohort. Patients …

Background: Patients with systemic lupus erythematosus (SLE) often suffer from obstetric
complications not necessarily associated with the antiphospholipid syndrome. These events …

Immune-inflammatory (autoimmune and autoinflammatory) rheumatic diseases are
widespread severe chronic inflammatory diseases and also “models” for studying the …