Functions of T cells in asthma: more than just TH2 cells

CM Lloyd, EM Hessel - Nature reviews immunology, 2010 - nature.com
Asthma has been considered a T helper 2 (TH2) cell-associated inflammatory disease, and
TH2-type cytokines, such as interleukin-4 (IL-4), IL-5 and IL-13, are thought to drive the …

Exercise and the aging immune system

RJ Simpson, TW Lowder, G Spielmann, AB Bigley… - Ageing research …, 2012 - Elsevier
Aging is associated with a decline in the normal functioning of the immune system that is
described by the canopy term “immunosenescence”. This contributes to poorer vaccine …

[HTML][HTML] Regulatory T cells in asthma

CM Lloyd, CM Hawrylowicz - Immunity, 2009 - cell.com
Asthma is characterized by T helper cell 2 (Th2) type inflammation, leading to airway
hyperresponsiveness and tissue remodeling. Th2 cell-driven inflammation is likely to …

Transforming growth factor‐beta1 in inflammatory airway disease: a key for understanding inflammation and remodeling

YC Yang, N Zhang, K Van Crombruggen, GH Hu… - Allergy, 2012 - Wiley Online Library
Airway diseases such as chronic rhinosinusitis, asthma, and chronic obstructive pulmonary
disorder are characterized by inflammation and remodeling. Among inflammatory and …

Regulatory T cells, inflammation and the allergic response—the role of glucocorticoids and vitamin D

S Dimeloe, A Nanzer, K Ryanna… - The Journal of steroid …, 2010 - Elsevier
Regulatory T cells (TRegs) play a central role in the maintenance of peripheral tolerance.
They prevent inappropriate immune responses to ubiquitous allergens in healthy …

Old Friends, immunoregulation, and stress resilience

D Langgartner, CA Lowry, SO Reber - Pflügers Archiv-European Journal …, 2019 - Springer
There is a considerable body of evidence indicating that chronic adverse experience,
especially chronic psychosocial stress/trauma, represents a major risk factor for the …

Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses

H Hammad, BN Lambrecht - Allergy, 2011 - Wiley Online Library
To cite this article: Hammad H, Lambrecht BN. Dendritic cells and airway epithelial cells at
the interface between innate and adaptive immune responses. Allergy 2011; 66: 579–587 …

Mechanisms and clinical implications of glucocorticosteroids in the treatment of allergic rhinitis

M Okano - Clinical & Experimental Immunology, 2009 - academic.oup.com
Allergic rhinitis is a common airway disease characterized by hypersensitivity, exudation,
hypersecretion, inflammatory cell infiltration and remodelling. Intranasal glucocorticosteroids …

Regulation of Th17/Treg function contributes to the attenuation of chronic airway inflammation by icariin in ovalbumin-induced murine asthma model

Y Wei, B Liu, J Sun, Y Lv, Q Luo, F Liu, J Dong - Immunobiology, 2015 - Elsevier
Icariin which is a flavonoid glucoside isolated from Epimedium brevicornu Maxim, has been
reported to have anti-osteoporotic, anti-inflammatory and anti-depressant-like activities. In …

LncRNA ANRIL/miR‐125a axis exhibits potential as a biomarker for disease exacerbation, severity, and inflammation in bronchial asthma

S Ye, S Zhu, L Feng - Journal of Clinical Laboratory Analysis, 2020 - Wiley Online Library
Background This study aimed to explore the correlation of lncRNA ANRIL/miR‐125a axis
with disease risk, severity, and inflammatory cytokines of bronchial asthma. Methods Plasma …