A common hallmark of age‐dependent neurodegenerative diseases is an impairment of
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …

The midbrain dopamine (mDA) system is composed of molecularly and functionally distinct
neuron subtypes that mediate specific behaviours and are linked to various brain diseases …

Retinoid X receptors (RXRs) present a subgroup of the nuclear receptor superfamily with
particularly high evolutionary conservation of ligand binding domain. The receptor exists in …

Wingless-type mouse mammary tumor virus (MMTV) integration site (Wnt) signaling is one of
the most critical pathways in developing and adult tissues. In the brain, Wnt signaling …

Since its discovery, Wnt signaling has been shown to be one of the most crucial
morphogens in development and during the maturation of central nervous system. Its action …

Neuroinflammatory processes are recognized key contributory factors in Parkinson's
disease (PD) physiopathology. While the causes responsible for the progressive loss of …

In Parkinson's disease (PD), substantia nigra (SN) dopaminergic (DA) neurons degenerate,
while related ventral tegmental area (VTA) DA neurons remain relatively unaffected. Here …

Dopaminergic neurons in the ventral mesencephalon (the ventral mesencephalic
dopaminergic complex) are known for their role in a multitude of behaviors, including …

During aging—one the most potent risk factors for Parkinson's disease (PD)—both
astrocytes and microglia undergo functional changes that ultimately hamper homoeostasis …

Glyphosate is the active ingredient in numerous herbicide formulations. The role of
glyphosate in neurotoxicity has been reported in human and animal models. However, the …