Biomarker-targeted therapies in non–small cell lung cancer: current status and perspectives

H Guo, J Zhang, C Qin, H Yan, T Liu, H Hu, S Tang… - Cells, 2022 - mdpi.com
Non-small-cell lung cancer (NSCLC) is one of the most common malignancies and the
leading causes of cancer-related death worldwide. Despite many therapeutic advances in …

Role of sex and sex hormones in PD-L1 expression in NSCLC: clinical and therapeutic implications

V Rodriguez-Lara, G Soca-Chafre… - Frontiers in …, 2023 - frontiersin.org
Currently, immunotherapy based on PD-1/PD-L1 pathway blockade has improved survival
of non-small cell lung cancer (NSCLC) patients. However, differential responses have been …

[HTML][HTML] Forskolin affects proliferation, migration and Paclitaxel-mediated cytotoxicity in non-small-cell lung cancer cell lines via adenylyl cyclase/cAMP axis

A Salzillo, A Ragone, A Spina, S Naviglio… - European Journal of Cell …, 2023 - Elsevier
Abstract Non-Small-Cell Lung Cancer (NSCLC) is considered one of the most frequently
diagnosed cancers and the leading cause of cancer-related deaths worldwide. Despite the …

TLR3 agonist nanoscale coordination polymer synergizes with immune checkpoint blockade for immunotherapy of cancer

Y Li, X Jiang, T Luo, J Xia, MJ Lee, RR Weichselbaum… - Biomaterials, 2022 - Elsevier
Immunotherapies including immune checkpoint blockade (ICB) have become integral to
treatments for immunogenic tumors by reinvigorating host immune functions to attack tumor …

Immunotherapy for metastatic non-small cell lung cancer: therapeutic advances and biomarkers

M Russano, G La Cava, A Cortellini, F Citarella… - Current …, 2023 - mdpi.com
Immunotherapy has revolutionized the treatment paradigm of non-small cell lung cancer and
improved patients' prognosis. Immune checkpoint inhibitors have quickly become standard …

A Biodegradable Nanosuspension Locally Used for Inhibiting Postoperative Recurrence and Brain Metastasis of Breast Cancer

M Qian, G Jiang, W Guo, R Huang - Nano Letters, 2024 - ACS Publications
Addressing the urgent need to prevent breast cancer postoperative recurrence and brain
metastasis, Fe-metal organic framework (MOF)-coated hollow mesoporous organosilica …

[HTML][HTML] Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation

D Cao, D Chen, JN Xia, WY Wang, GY Zhu… - Biomedicine & …, 2022 - Elsevier
Highlights•Artesunate inhibited the expression of TAZ and PD-L1 in NSCLC.•Artesunate
suppressed TAZ/PD-L1-induced T-cell growth inhibition.•Artesunate enhanced anti-tumor …

Cancer immunotherapy: Fecal microbiota transplantation brings light

J Zhang, K Wu, C Shi, G Li - Current Treatment Options in Oncology, 2022 - Springer
Opinion statement Immunotherapy is revolutionizing tumor treatment by activating the
immune response to tumors. Among them, immunotherapy represented by immune …

Predictive value of baseline FDG-PET/CT for the durable response to immune checkpoint inhibition in NSCLC patients using the morphological and metabolic features …

K Kudura, N Ritz, T Kutzker, MHK Hoffmann… - Cancers, 2022 - mdpi.com
Simple Summary Lung cancer is the leading cause of cancer-related death worldwide.
Nonsmall cell lung cancer (NSCLC) accounts for 80–85% of all cases. Immune checkpoint …

Withaferin a increases the effectiveness of immune checkpoint blocker for the treatment of non-small cell lung cancer

R Khalil, RJ Green, K Sivakumar, P Varandani… - Cancers, 2023 - mdpi.com
Simple Summary Lung cancer is the leading cause of cancer-related deaths.
Immunotherapy activates the patient's immune system to identify and kill cancer cells …