Indications for haematopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2019

RF Duarte, M Labopin, P Bader, GW Basak… - Bone marrow …, 2019 - nature.com
This is the seventh special EBMT report on the indications for haematopoietic stem cell
transplantation for haematological diseases, solid tumours and immune disorders. Our aim …

Minimal residual disease diagnostics in acute lymphoblastic leukemia: need for sensitive, fast, and standardized technologies

JJM van Dongen, VHJ van der Velden… - Blood, The Journal …, 2015 - ashpublications.org
Monitoring of minimal residual disease (MRD) has become routine clinical practice in
frontline treatment of virtually all childhood acute lymphoblastic leukemia (ALL) and in many …

[HTML][HTML] Indications for haematopoietic cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2022

JA Snowden, I Sánchez-Ortega… - Bone marrow …, 2022 - nature.com
For over two decades, the EBMT has updated recommendations on indications for
haematopoietic cell transplantation (HCT) practice based on clinical and scientific …

Next-generation sequencing of minimal residual disease for predicting relapse after tisagenlecleucel in children and young adults with acute lymphoblastic leukemia

MA Pulsipher, X Han, SL Maude, TW Laetsch… - Blood cancer …, 2022 - AACR
We assessed minimal residual disease (MRD) detection and B-cell aplasia after
tisagenlecleucel therapy for acute lymphoblastic leukemia (ALL) to define biomarkers …

Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia

V Frismantas, MP Dobay, A Rinaldi… - Blood, The Journal …, 2017 - ashpublications.org
Drug sensitivity and resistance testing on diagnostic leukemia samples should provide
important functional information to guide actionable target and biomarker discovery. We …

[HTML][HTML] Stem-cell transplantation in children with acute lymphoblastic leukemia: A prospective international multicenter trial comparing sibling donors with matched …

C Peters, M Schrappe, A von Stackelberg… - Journal of clinical …, 2015 - folia.unifr.ch
Although hematopoietic stem-cell transplantation is widely performed in children with high-
risk acute lymphoblastic leukemia (ALL), the influence of donor types is poorly understood …

[HTML][HTML] Minimal residual disease in acute lymphoblastic leukemia: technical and clinical advances

I Della Starza, S Chiaretti, MS De Propris, L Elia… - Frontiers in …, 2019 - frontiersin.org
Introduction: Acute lymphoblastic leukemia (ALL) is the first neoplasm where the
assessment of early response to therapy by minimal residual disease (MRD) monitoring has …

IgH-V (D) J NGS-MRD measurement pre-and early post-allotransplant defines very low-and very high-risk ALL patients

MA Pulsipher, C Carlson, B Langholz… - Blood, The Journal …, 2015 - ashpublications.org
Positive detection of minimal residual disease (MRD) by multichannel flow cytometry (MFC)
prior to hematopoietic cell transplantation (HCT) of patients with acute lymphoblastic …

Minimal residual disease in adult ALL: technical aspects and implications for correct clinical interpretation

M Brüggemann, M Kotrova - Hematology 2014, the American …, 2017 - ashpublications.org
Nowadays, minimal residual disease (MRD) is accepted as the strongest independent
prognostic factor in acute lymphoblastic leukemia (ALL). It can be detected by molecular …

[HTML][HTML] Minimal residual disease detection in acute lymphoblastic leukemia

A Kruse, N Abdel-Azim, HN Kim, Y Ruan… - International journal of …, 2020 - mdpi.com
Minimal residual disease (MRD) refers to a chemotherapy/radiotherapy-surviving leukemia
cell population that gives rise to relapse of the disease. The detection of MRD is critical for …