Age and sex are critical factors in ischemic stroke pathology
M Roy-O'Reilly, LD McCullough - Endocrinology, 2018 - academic.oup.com
Ischemic stroke is a devastating brain injury resulting in high mortality and substantial loss of
function. Understanding the pathophysiology of ischemic stroke risk, mortality, and functional …
function. Understanding the pathophysiology of ischemic stroke risk, mortality, and functional …
Sex‐related differences in contemporary biomarkers for heart failure: a review
N Suthahar, LMG Meems, JE Ho… - European journal of …, 2020 - Wiley Online Library
The use of circulating biomarkers for heart failure (HF) is engrained in contemporary
cardiovascular practice and provides objective information about various pathophysiological …
cardiovascular practice and provides objective information about various pathophysiological …
Adrenomedullin induces cardiac lymphangiogenesis after myocardial infarction and regulates cardiac edema via connexin 43
CE Trincot, W Xu, H Zhang, MR Kulikauskas… - Circulation …, 2019 - Am Heart Assoc
Rationale: Cardiac lymphangiogenesis contributes to the reparative process post-
myocardial infarction, but the factors and mechanisms regulating it are not well understood …
myocardial infarction, but the factors and mechanisms regulating it are not well understood …
Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and …
Ischaemic heart disease (IHD) is a complex disorder and a leading cause of death and
morbidity in both men and women. Sex, however, affects several aspects of IHD, including …
morbidity in both men and women. Sex, however, affects several aspects of IHD, including …
Estrogen regulation of microRNA expression
CM Klinge - Current genomics, 2009 - ingentaconnect.com
Women outlive men, but life expectancy is not influenced by hormone replacement
(estrogen+ progestin) therapy. Estrogens appear to protect brain, cardiovascular tissues …
(estrogen+ progestin) therapy. Estrogens appear to protect brain, cardiovascular tissues …
Genistein, a soy phytoestrogen, reverses severe pulmonary hypertension and prevents right heart failure in rats
Pretreatment with a phytoestrogen genistein has been shown to attenuate the development
of pulmonary hypertension (PH). Because PH is not always diagnosed early, we examined …
of pulmonary hypertension (PH). Because PH is not always diagnosed early, we examined …
Genetic and epigenetic factors of Takotsubo syndrome: a systematic review
V Ferradini, D Vacca, B Belmonte, R Mango… - International Journal of …, 2021 - mdpi.com
Takotsubo syndrome (TTS), recognized as stress's cardiomyopathy, or as left ventricular
apical balloon syndrome in recent years, is a rare pathology, described for the first time by …
apical balloon syndrome in recent years, is a rare pathology, described for the first time by …
[HTML][HTML] Female cardiovascular biology and resilience in the setting of physiological and pathological stress
HE Collins - Redox Biology, 2023 - Elsevier
For years, females were thought of as smaller men with complex hormonal cycles; as a
result, females have been largely excluded from preclinical and clinical research. However …
result, females have been largely excluded from preclinical and clinical research. However …
[HTML][HTML] Pathophysiology of Takotsubo syndrome
Transient left ventricular (LV) apical ballooning syndrome, Takotsubo cardiomyopathy,
Takotsubo syndrome (TTS), broken heart syndrome, ampulla cardiomyopathy, or stress …
Takotsubo syndrome (TTS), broken heart syndrome, ampulla cardiomyopathy, or stress …
Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice
GR Jenkins, T Lee, CL Moland, V Vijay… - Toxicology and Applied …, 2016 - Elsevier
Sex is a risk factor for development of cardiotoxicity, induced by the anti-cancer drug,
doxorubicin (DOX), in humans. To explore potential mechanisms underlying differential …
doxorubicin (DOX), in humans. To explore potential mechanisms underlying differential …