Polycystic ovary syndrome: a comprehensive review of pathogenesis, management, and drug repurposing
Polycystic ovary syndrome (PCOS) is an endocrine-gynecology disorder affecting many
women of childbearing age. Although a part of the involved mechanism in PCOS occurrence …
women of childbearing age. Although a part of the involved mechanism in PCOS occurrence …
[HTML][HTML] Resveratrol for cancer therapy: Challenges and future perspectives
B Ren, MXY Kwah, C Liu, Z Ma, MK Shanmugam… - Cancer letters, 2021 - Elsevier
Abstract Resveratrol (3, 4', 5-trihydroxy-trans-stilbene) has been expected to ameliorate
cancer and foster breakthroughs in cancer therapy. Despite thousands of preclinical studies …
cancer and foster breakthroughs in cancer therapy. Despite thousands of preclinical studies …
Health benefits of resveratrol: Evidence from clinical studies
AP Singh, R Singh, SS Verma, V Rai… - Medicinal research …, 2019 - Wiley Online Library
Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …
The therapeutic potential of resveratrol: a review of clinical trials
AY Berman, RA Motechin, MY Wiesenfeld… - NPJ precision …, 2017 - nature.com
Resveratrol is a nutraceutical with several therapeutic effects. It has been shown to mimic
effects of caloric restriction, exert anti-inflammatory and anti-oxidative effects, and affect the …
effects of caloric restriction, exert anti-inflammatory and anti-oxidative effects, and affect the …
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
MS Bonkowski, DA Sinclair - Nature reviews Molecular cell biology, 2016 - nature.com
Abstract The sirtuins (SIRT1–7) are a family of nicotinamide adenine dinucleotide (NAD+)-
dependent deacylases with remarkable abilities to prevent diseases and even reverse …
dependent deacylases with remarkable abilities to prevent diseases and even reverse …
Antioxidant effects of resveratrol in the cardiovascular system
The antioxidant effects of resveratrol (3, 5, 4'‐trihydroxy‐trans‐stilbene) contribute
substantially to the health benefits of this compound. Resveratrol has been shown to be a …
substantially to the health benefits of this compound. Resveratrol has been shown to be a …
Properties of Resveratrol: In Vitro and In Vivo Studies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans
Plants containing resveratrol have been used effectively in traditional medicine for over
2000 years. It can be found in some plants, fruits, and derivatives, such as red wine …
2000 years. It can be found in some plants, fruits, and derivatives, such as red wine …
Mechanisms of aging and the preventive effects of resveratrol on age-related diseases
IS Pyo, S Yun, YE Yoon, JW Choi, SJ Lee - Molecules, 2020 - mdpi.com
Aging gradually decreases cellular biological functions and increases the risk of age-related
diseases. Cancer, type 2 diabetes mellitus, cardiovascular disease, and neurological …
diseases. Cancer, type 2 diabetes mellitus, cardiovascular disease, and neurological …
Effect of resveratrol and pterostilbene on aging and longevity
YR Li, S Li, CC Lin - Biofactors, 2018 - Wiley Online Library
Over the past years, several studies have found that foods rich in polyphenols protect
against age‐related disease, such as atherosclerosis, cardiovascular disease, cancer …
against age‐related disease, such as atherosclerosis, cardiovascular disease, cancer …
Mediterranean diet nutrients to turn the tide against insulin resistance and related diseases
M Mirabelli, E Chiefari, B Arcidiacono, DM Corigliano… - Nutrients, 2020 - mdpi.com
Insulin resistance (IR), defined as an attenuated biological response to circulating insulin, is
a fundamental defect in obesity and type 2 diabetes (T2D), and is also linked to a wide …
a fundamental defect in obesity and type 2 diabetes (T2D), and is also linked to a wide …