Ferritin‐Hijacking Nanoparticles Spatiotemporally Directing Endogenous Ferroptosis for Synergistic Anticancer Therapy
L Zhu, Y You, M Zhu, Y Song, J Zhang, J Hu… - Advanced …, 2022 - Wiley Online Library
Existing ferroptosis as an iron‐dependent form of regulated cell death primarily relies on
importing exogenous iron. However, the excessive employment of toxic materials may cause …
importing exogenous iron. However, the excessive employment of toxic materials may cause …
Hydrogel-based dressings designed to facilitate wound healing
W Zhang, L Liu, H Cheng, J Zhu, X Li, S Ye, X Li - Materials Advances, 2024 - pubs.rsc.org
The escalating prevalence of wounds, particularly chronic wounds, poses significant
challenges in terms of treatment management and has led to an increase in healthcare …
challenges in terms of treatment management and has led to an increase in healthcare …
[HTML][HTML] The rare-earth yttrium induces cell apoptosis and autophagy in the male reproductive system through ROS-Ca2+-CamkII/Ampk axis
F Hou, J Huang, F Qing, T Guo, S Ouyang, L Xie… - Ecotoxicology and …, 2023 - Elsevier
China has the world's largest reserves of rare earth elements (REEs), but widespread
mining and application of REEs has led to an increased risk of potential pollution. Yttrium …
mining and application of REEs has led to an increased risk of potential pollution. Yttrium …
DNA damage-encouraged Mn-As-based nanoreactors reshape intratumoral cell phenotypes to recover immune surveillance and potentiate anti-tumor immunity
Q Zhao, X Dong, C Zhu, Y Zhang, C Fang… - Chemical Engineering …, 2023 - Elsevier
Arsenic trioxide is a promising anti-tumor approach based on cytotoxic reactive oxygen
species (ROS). However, the harsh post-encapsulation conditions, complex tumor …
species (ROS). However, the harsh post-encapsulation conditions, complex tumor …
Yttrium oxide nanoparticles induce cytotoxicity, genotoxicity, apoptosis, and ferroptosis in the human triple-negative breast cancer MDA-MB-231 cells
Background Triple-negative breast cancer (TNBC) is a lethal mammary carcinoma subtype
that affects females and is associated with a worse prognosis. Chemotherapy is the only …
that affects females and is associated with a worse prognosis. Chemotherapy is the only …
[HTML][HTML] Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse …
L Xiong, J Huang, C Wu, Q Yuan, S Wang, L Zhu… - Ecotoxicology and …, 2023 - Elsevier
The growing presence of yttrium (Y) in the environment raises concern regarding its safety
and toxicity. However, limited toxicological data are available to determine cardiotoxicity of Y …
and toxicity. However, limited toxicological data are available to determine cardiotoxicity of Y …
CPT2-mediated fatty acid oxidation inhibits tumorigenesis and enhances sorafenib sensitivity via the ROS/PPARγ/NF-κB pathway in clear cell renal cell carcinoma
K Zeng, Q Li, G Song, B Chen, M Luo, J Miao, B Liu - Cellular Signalling, 2023 - Elsevier
Kidney cancer is a common kind of tumor with approximately 400,000 new diagnoses each
year. Clear cell renal cell carcinoma (ccRCC) accounts for 70–80% of all renal cell …
year. Clear cell renal cell carcinoma (ccRCC) accounts for 70–80% of all renal cell …
Nrf2 prevents diabetic cardiomyopathy via antioxidant effect and normalization of glucose and lipid metabolism in the heart
G Yang, Q Zhang, C Dong, G Hou, J Li… - Journal of Cellular …, 2024 - Wiley Online Library
Metabolic disorders and oxidative stress are the main causes of diabetic cardiomyopathy.
Activation of nuclear factor erythroid 2‐related factor 2 (Nrf2) exerts a powerful antioxidant …
Activation of nuclear factor erythroid 2‐related factor 2 (Nrf2) exerts a powerful antioxidant …
Association between concentrations of rare earth elements in chorionic villus and risk for unexplained spontaneous abortion
M Lin, L Yan, X Wang, Y Wang, Y Zhou, L Wang… - Environmental …, 2024 - Elsevier
Rare earth elements (REEs) exposure during pregnancy may increase the risk of
unexplained spontaneous abortion. However, the association between REEs intrauterine …
unexplained spontaneous abortion. However, the association between REEs intrauterine …
Tl (I) and Tl (III)-induce genotoxicity, reticulum stress and autophagy in PC12 Adh cells
DM Salvatierra-Fréchou, SV Verstraeten - Archives of Toxicology, 2024 - Springer
Thallium (Tl) and its two cationic species, Tl (I) and Tl (III), are toxic for most living beings. In
this work, we investigated the effects of Tl (10–100 µM) on the viability and proliferation …
this work, we investigated the effects of Tl (10–100 µM) on the viability and proliferation …