Reactive oxygen species (ROS) serve as cell signaling molecules generated in oxidative
metabolism and are associated with a number of human diseases. The reprogramming of …

Oxidative stress (OS), defined as redox imbalance in favor of oxidant burden, is one of the
most significant biological events in cancer progression. Cancer cells generally represent a …

Brachytherapy is a specific form of radiotherapy consisting of the precise placement of
radioactive sources directly into or next to the tumor. This technique is indicated for patients …

Noncoding RNAs (ncRNAs) represent a large segment of the human transcriptome and
have been shown to play important roles in cellular physiology and disease pathogenesis …

Radiotherapy (RT) is a modality of oncologic treatment that can be used to treat
approximately 50% of all cancer patients either alone or in combination with other treatment …

Owing to advances in radiotherapy, the physical properties of radiation can be optimized to
enable individualized treatment; however, optimization is rarely based on biological …

Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …

Mitochondria are intracellular organelles involved in energy production, cell metabolism and
cell signaling. They are essential not only in the process of ATP synthesis, lipid metabolism …

Colorectal cancer is one of the most common cancers worldwide with high mortality. Distant
metastasis and relapse are major causes of patient death. Cancer stem cells (CSCs) play a …

Immune checkpoint therapy has achieved significant efficacy by blocking inhibitory
pathways to release the function of T lymphocytes. In the clinic, anti-programmed cell death …