Elastography has emerged as a preferred non-invasive imaging technique for the clinical
assessment of liver fibrosis. Elastography methods provide liver stiffness measurement …

Non-invasive evaluation of liver fibrosis has evolved over the last couple of decades.
Currently, elastography techniques are the most widely used non-invasive methods for …

Background & Aims Efruxifermin has shown clinical efficacy in patients with non-alcoholic
steatohepatitis (NASH) and F1–F3 fibrosis. The primary objective of the BALANCED Cohort …

Purpose: Cancer-associated fibroblasts have emerged to be highly heterogenous and can
play multifaceted roles in dictating pancreatic ductal adenocarcinoma (PDAC) progression …

Nonalcoholic steatohepatitis (NASH) is one of the most common chronic liver diseases in
the world, yet no pharmacotherapies are available. The lack of translational animal models …

Accurate detection and quantification of hepatic fibrosis remain essential for assessing the
severity of non-alcoholic fatty liver disease (NAFLD) and its response to therapy in clinical …

The development of rapid and accurate Whole Slide Imaging (WSI) has paved the way for
the application of Artificial Intelligence (AI) to digital pathology. The availability of WSI in the …

Background Colorectal cancer (CRC) is the most common cancer and a leading cause of
death worldwide. Extracellular matrix (ECM) proteins regulate tumor growth and …

Liver fibrosis (LF) is the wound healing response to chronic liver injury. LF is the endpoint of
chronic liver disease (CLD) regardless of etiology and the single most important determinant …

Background Collagen proportionate area (CPA) measurement is a technique that quantifies
fibrous tissue in liver biopsies by measuring the amount of collagen deposition as a …