Characterization of cyanobacterial hydrocarbon composition and distribution of biosynthetic pathways

RC Coates, S Podell, A Korobeynikov, A Lapidus… - PloS one, 2014 - journals.plos.org
Cyanobacteria possess the unique capacity to naturally produce hydrocarbons from fatty
acids. Hydrocarbon compositions of thirty-two strains of cyanobacteria were characterized to …

Accelerating strain engineering in biofuel research via build and test automation of synthetic biology

J Zhang, Y Chen, L Fu, E Guo, B Wang, L Dai… - Current Opinion in …, 2021 - Elsevier
Highlights•The lack of predictive modeling limits biosystems design for biofuel production.•
Automation in build and test accelerates strain engineering for biofuel research.•Microplates …

Generation of an atlas for commodity chemical production in Escherichia coli and a novel pathway prediction algorithm, GEM-Path

MA Campodonico, BA Andrews, JA Asenjo… - Metabolic …, 2014 - Elsevier
The production of 75% of the current drug molecules and 35% of all chemicals could be
achieved through bioprocessing (Arundel and Sawaya, 2009). To accelerate the transition …

In pursuit of Sustainable Development Goal (SDG) number 7: Will biofuels be reliable?

M Acheampong, FC Ertem, B Kappler… - … and sustainable energy …, 2017 - Elsevier
Driven by the desire to mitigate climate change and reduce overdependence on fossil fuels,
biofuels have been actively pursued in recent years because they are believed to be …

Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli

TP Howard, S Middelhaufe, K Moore… - Proceedings of the …, 2013 - National Acad Sciences
Biofuels are the most immediate, practical solution for mitigating dependence on fossil
hydrocarbons, but current biofuels (alcohols and biodiesels) require significant downstream …

[HTML][HTML] Metabolic engineering for the high-yield production of isoprenoid-based C5 alcohols in E. coli

KW George, MG Thompson, A Kang, E Baidoo… - Scientific reports, 2015 - nature.com
Branched five carbon (C 5) alcohols are attractive targets for microbial production due to
their desirable fuel properties and importance as platform chemicals. In this study, we …

Methylobacterium extorquens: methylotrophy and biotechnological applications

AM Ochsner, F Sonntag, M Buchhaupt… - Applied Microbiology …, 2015 - Springer
Methylotrophy is the ability to use reduced one-carbon compounds, such as methanol, as a
single source of carbon and energy. Methanol is, due to its availability and potential for …

Engineering endogenous ABC transporter with improving ATP supply and membrane flexibility enhances the secretion of β-carotene in Saccharomyces cerevisiae

X Bu, JY Lin, J Cheng, D Yang, CQ Duan… - Biotechnology for …, 2020 - Springer
Background Product toxicity is one of the bottlenecks for microbial production of biofuels,
and transporter-mediated biofuel secretion offers a promising strategy to solve this problem …

Plant diterpene synthases: exploring modularity and metabolic diversity for bioengineering

P Zerbe, J Bohlmann - Trends in biotechnology, 2015 - cell.com
Plants produce thousands of diterpenoid natural products; some of which are of significant
industrial value as biobased pharmaceuticals (taxol), fragrances (sclareol), food additives …

Fatty acid biosynthesis: chain‐length regulation and control

CS Heil, SS Wehrheim, KS Paithankar… - …, 2019 - Wiley Online Library
De novo biosynthesis of fatty acids is an iterative process requiring strict regulation of the
lengths of the produced fatty acids. In this review, we focus on the factors determining chain …