Internal dosimetry for TARE therapies by means of GAMOS Monte Carlo simulations

L Auditore, E Amato, A Italiano, P Arce, A Campennì… - Physica Medica, 2019 - Elsevier
Three-dimensional internal dosimetry is increasingly used in planning Trans-Arterial Radio-
Embolization (TARE) of HepatoCellular Carcinoma (HCC). Among the existing calculation …

Concepts and methods for the dosimetry of radioembolisation of the liver with Y-90-loaded microspheres

A Dieudonné, M Sanchez-Garcia… - Frontiers in Nuclear …, 2022 - frontiersin.org
This article aims at presenting in a didactic way, dosimetry concepts and methods that are
relevant for radio-embolization of the liver with 90Y-microspheres. The application of the …

Full Monte Carlo internal dosimetry in nuclear medicine by means of GAMOS

E Amato, L Auditore, A Italiano, D Pistone… - Journal of Physics …, 2020 - iopscience.iop.org
Three-dimensional internal dosimetry is increasingly used in diagnostic and therapeutic
nuclear medicine. Even if simplified calculation approaches are currently available, the full …

Clinical Evaluation of a Three-Dimensional Internal Dosimetry Technique for Liver Radioembolization with 90Y Microspheres Using Dose Voxel Kernels

D Plachouris, KA Mountris… - Cancer Biotherapy & …, 2021 - liebertpub.com
Background: The purpose of this study was to develop a rapid, reliable, and efficient tool for
three-dimensional (3D) dosimetry treatment planning and post-treatment evaluation of liver …

Monte Carlo 90Y PET/CT dosimetry of unexpected focal radiation-induced lung damage after hepatic radioembolisation

L Auditore, E Amato, S Boughdad… - Physics in Medicine …, 2020 - iopscience.iop.org
Transarterial radioembolization (TARE) with 90 Y-loaded microspheres is an established
therapeutic option for inoperable hepatic tumors. Increasing knowledge regarding TARE …

Comparative Study of the Effect of Radiation Delivered by Lutetium-177 or Actinium-225 on Anti-GD2 Chimeric Antigen Receptor T Cell Viability and Functions

QH Sodji, MH Forsberg, D Cappabianca, CP Kerr… - Cancers, 2023 - mdpi.com
Simple Summary Low-dose radiation delivered by radionuclides stimulates an immune
response against cancer. We hypothesize that this type of low-dose radiation can potentiate …

Theranostics and Patient-Specific Dosimetry

B Bednarz - Seminars in Radiation Oncology, 2023 - Elsevier
Radiopharmaceutical therapy (RPT) is an invigorated form of cancer therapy that
systemically delivers targeted radioactive drugs to cancer cells. Theranostics is a type of …

Quantification of internal dosimetry in PET patients: individualized Monte Carlo vs generic phantom‐based calculations

S Neira, J Guiu‐Souto, P Díaz‐Botana, P Pais… - Medical …, 2020 - Wiley Online Library
Purpose The purpose of this work is to calculate individualized dose distributions in patients
undergoing 18F‐FDG PET/CT studies through a methodology based on full Monte Carlo …

The role of companion animal models in radiopharmaceutical development and translation

CA Maitz, JN Bryan - Veterinary and Comparative Oncology, 2024 - Wiley Online Library
Advancements in molecular imaging and drug targeting have created a renaissance in the
development of radiopharmaceuticals for therapy and theranostics. While some …

Targeting of head and neck cancer by radioiodinated CLR1404 in murine xenograft tumor models with partial volume corrected theranostic dosimetry

IR Marsh, C Li, J Grudzinski, J Jeffery… - Cancer Biotherapy & …, 2023 - liebertpub.com
Background: Delivery of radiotherapeutic dose to recurrent head and neck cancer (HNC) is
primarily limited by locoregional toxicity in conventional radiotherapy. As such, HNC patients …