Targeting immunometabolism as an anti-inflammatory strategy
EM Pålsson-McDermott, LAJ O'Neill - Cell research, 2020 - nature.com
The growing field of immunometabolism has taught us how metabolic cellular reactions and
processes not only provide a means to generate ATP and biosynthetic precursors, but are …
processes not only provide a means to generate ATP and biosynthetic precursors, but are …
Nitric oxide function in plant biology: a redox cue in deconvolution
Nitric oxide (NO), a gaseous, redox‐active small molecule, is gradually becoming
established as a central regulator of growth, development, immunity and environmental …
established as a central regulator of growth, development, immunity and environmental …
How does the multifaceted plant hormone salicylic acid combat disease in plants and are similar mechanisms utilized in humans?
DMA Dempsey, DF Klessig - BMC biology, 2017 - Springer
Salicylic acid (SA) is an important plant hormone that regulates many aspects of plant
growth and development, as well as resistance to (a) biotic stress. Efforts to identify SA …
growth and development, as well as resistance to (a) biotic stress. Efforts to identify SA …
The scientific and clinical basis for the treatment of Parkinson disease (2009)
CW Olanow, MB Stern, K Sethi - Neurology, 2009 - AAN Enterprises
Parkinson disease (PD) is an age-related neurodegenerative disorder that affects as many
as 1–2% of persons aged 60 years and older. With the aging of the population, the …
as 1–2% of persons aged 60 years and older. With the aging of the population, the …
The diverse functions of GAPDH: views from different subcellular compartments
C Tristan, N Shahani, TW Sedlak, A Sawa - Cellular signalling, 2011 - Elsevier
Multiple roles for glyceraldehyde-3-phosphate dehydrogenase (GAPDH) have been recently
appreciated. In addition to the cytoplasm where the majority of GAPDH is located under the …
appreciated. In addition to the cytoplasm where the majority of GAPDH is located under the …
NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences
W Ying - Antioxidants & redox signaling, 2008 - liebertpub.com
C. NADP synthesis D. Catabolism of NAD and NADP E. Relationships between NAD and
NADP F. NAD transport across mitochondrial membranes G. NAD transport across the …
NADP F. NAD transport across mitochondrial membranes G. NAD transport across the …
Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity
V Calabrese, C Mancuso, M Calvani… - Nature reviews …, 2007 - nature.com
At the end of the 1980s, it was clearly demonstrated that cells produce nitric oxide and that
this gaseous molecule is involved in the regulation of the cardiovascular, immune and …
this gaseous molecule is involved in the regulation of the cardiovascular, immune and …
[HTML][HTML] Aberrant protein s-nitrosylation in neurodegenerative diseases
T Nakamura, S Tu, MW Akhtar, CR Sunico, S Okamoto… - Neuron, 2013 - cell.com
S-Nitrosylation is a redox-mediated posttranslational modification that regulates protein
function via covalent reaction of nitric oxide (NO)-related species with a cysteine thiol group …
function via covalent reaction of nitric oxide (NO)-related species with a cysteine thiol group …
Protein S-nitrosylation in health and disease: a current perspective
Protein S-nitrosylation constitutes a large part of the ubiquitous influence of nitric oxide on
cellular signal transduction and accumulating evidence indicates important roles for S …
cellular signal transduction and accumulating evidence indicates important roles for S …
[HTML][HTML] Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer …
KO Alfarouk, D Verduzco, C Rauch, AK Muddathir… - …, 2014 - ncbi.nlm.nih.gov
Cancer cells acquire an unusual glycolytic behavior relative, to a large extent, to their
intracellular alkaline pH (pH i). This effect is part of the metabolic alterations found in most, if …
intracellular alkaline pH (pH i). This effect is part of the metabolic alterations found in most, if …