Periodontitis is a common intraoral infection and is inextricably linked to systemic diseases.
Recently, the regulation between host immunologic response and periodontal pathogens …

Lipopolysaccharides (LPS) of Gram negative bacteria are one of the most potent stimulators
of the host innate immune system and LPS recognition is essential for the host organism to …

Interferon (IFN)-Is are crucial mediators of antiviral immunity and homeostatic immune
system regulation. However, the source of IFN-I signaling under homeostatic conditions is …

During the course of evolution, multicellular organisms have been orchestrated with an
efficient and versatile immune system to counteract diverse group of pathogenic organisms …

Lipopolysaccharide (LPS) is a major component of the outer membrane of Gram-negative
bacteria. Minute amounts of LPS released from infecting pathogens can initiate potent innate …

Obesity is a major risk factor for the development of various pathological conditions
including insulin resistance, diabetes, cardiovascular diseases, and non-alcoholic fatty liver …

The gut microbiome has emerged as a critical regulator of human physiology. Deleterious
changes to the composition or number of gut bacteria, commonly referred to as gut …

The receptors of the innate immune system detect specific microbial ligands to promote
effective inflammatory and adaptive immune responses. Although this idea is well …

Lipopolysaccharide (LPS) of Gram-negative bacteria can elicit a strong immune response.
Although extracellular LPS is sensed by TLR4 at the cell surface and triggers a …

The human gastrointestinal tract harbors a heterogeneous and complex microbial
community, which plays a key role in human health. The gut microbiota controls the …