[HTML][HTML] Immunometabolic factors contributing to obesity-linked hepatocellular carcinoma
MG Akl, SB Widenmaier - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) is a major public health concern that is promoted by
obesity and associated liver complications. Onset and progression of HCC in obesity is a …
obesity and associated liver complications. Onset and progression of HCC in obesity is a …
siRNA-mediated gene silencing for non-alcoholic fatty liver disease: A comprehensive review of molecular targets
A Mahmoudi, M Rostami, MM Hajihasani… - European Polymer …, 2024 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a burgeoning global public health distress, with
an estimated 25% of the world population affected. Despite the increasing prevalence and …
an estimated 25% of the world population affected. Despite the increasing prevalence and …
[HTML][HTML] Resmetirom ameliorates NASH-model mice by suppressing STAT3 and NF-κB signaling pathways in an RGS5-dependent manner
X Wang, L Wang, L Geng, N Tanaka, B Ye - International Journal of …, 2023 - mdpi.com
Resmetirom, a liver-directed, orally active agonist of THR-β, could play a favorable role in
treating NASH, but little is known about the underlying mechanism. A NASH cell model was …
treating NASH, but little is known about the underlying mechanism. A NASH cell model was …
[HTML][HTML] Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NF-κB pathway
BF Yan, LF Pan, YF Quan, Q Sha… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Nonalcoholic fatty liver disease (NAFLD) is a clinicopathological entity
characterized by intrahepatic ectopic steatosis. As a consequence of increased consumption …
characterized by intrahepatic ectopic steatosis. As a consequence of increased consumption …
[HTML][HTML] Metabolic dysfunction-associated steatotic liver disease: An opportunity for collaboration between cardiology and hepatology
Altered metabolic function has many detrimental effects on the body that can manifest as
cardiovascular and liver diseases. Traditional approaches to understanding and treating …
cardiovascular and liver diseases. Traditional approaches to understanding and treating …
[HTML][HTML] Esculeogenin A, a Glycan from Tomato, Alleviates Nonalcoholic Fatty Liver Disease in Rats through Hypolipidemic, Antioxidant, and Anti-Inflammatory Effects
JM Al Jadani, NA Albadr, GM Alshammari, SA Almasri… - Nutrients, 2023 - mdpi.com
This study examined the preventative effects of esculeogenin A (ESGA), a newly discovered
glycan from tomato, on liver damage and hepatic steatosis in high-fat-diet (HFD)-fed male …
glycan from tomato, on liver damage and hepatic steatosis in high-fat-diet (HFD)-fed male …
Analysis of the therapeutic potential of miR-124 and miR-16 in non-alcoholic fatty liver disease
Backgrounds Non-alcoholic fatty liver disease (NAFLD) is a common condition affecting>
25% of the population worldwide. This disorder ranges in severity from simple steatosis (fat …
25% of the population worldwide. This disorder ranges in severity from simple steatosis (fat …
[HTML][HTML] Fenofibrate alleviates NAFLD by enhancing the PPARα/PGC-1α signaling pathway coupling mitochondrial function
X Wang, J Wang, C Ying, Y Xing, X Su… - BMC Pharmacology and …, 2024 - Springer
Background To comprehend the influences of fenofibrate on hepatic lipid accumulation and
mitochondrial function-related signaling pathways in mice with non-alcoholic fatty liver …
mitochondrial function-related signaling pathways in mice with non-alcoholic fatty liver …
[HTML][HTML] Capparis spinosa improves non-alcoholic steatohepatitis through down-regulating SREBP-1c and a PPARα-independent pathway in high-fat diet-fed rats
Objective Non-alcoholic steatohepatitis (NASH) has become a global medical problem.
Currently, there is no approved pharmacologic treatment for this condition. Previous studies …
Currently, there is no approved pharmacologic treatment for this condition. Previous studies …
Current and experimental pharmacotherapy for the management of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease, with its incidence
increasing in parallel with the global prevalence of obesity and type 2 diabetes mellitus …
increasing in parallel with the global prevalence of obesity and type 2 diabetes mellitus …