New discoveries in drugs and drug delivery systems are focused on identifying and
delivering a pharmacologically effective agent, potentially targeting a specific molecular …

Currently there are approximately 291,000 people suffering from a spinal cord injury (SCI) in
the United States. SCI is associated with traumatic changes in mobility and neuralgia, as …

Traumatic brain injury (TBI) heavily impacts the body: it damages the brain tissue and the
peripheral nervous system and shifts homeostasis in many types of tissue. An acute brain …

Given the increase in life expectancy, aging with a pre-existing spinal cord injury (SCI) is
becoming more common. This condition is challenging as compromised health status and …

Spinal cord injury is a traumatic lesion that causes a catastrophic condition in patients,
resulting in neuronal deficit and loss of motor and sensory function. That loss is caused by …

Highlights•The developmental trajectory of the microbiota coincides with CNS myelination
and the onset of neurodevelopmental disorders.•The microbiota-gut-brain axis facilitates …

Traumatic brain injury and spinal cord injury are two distinct but fundamentally similar types
of acute insults to the central nervous system (CNS) that often culminate in death or …

A spinal cord injury (SCI) can result in varying degrees of limb movement impairment and
sensory impairment, affecting the quality of life severely. The study of the molecular …

Chronic pain is a common medical complication experienced by those living with spinal cord
injury (SCI) and leads to worsened quality of life. The pathophysiology of SCI pain is poorly …

There has been a rapid increase in neonates born with a history of prenatal opioid
exposure. How prenatal opioid exposure affects pain sensitivity in offspring is of interest, as …