Hepatocellular carcinoma (HCC): Epidemiology, etiology and molecular classification
S Chidambaranathan-Reghupaty, PB Fisher… - Advances in cancer …, 2021 - Elsevier
Hepatocellular carcinoma (HCC), the primary malignancy of hepatocytes, is a diagnosis with
bleak outcome. According to National Cancer Institute's SEER database, the average five …
bleak outcome. According to National Cancer Institute's SEER database, the average five …
Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
[HTML][HTML] Approaches, progress, and challenges to hepatitis C vaccine development
Risk factors for hepatitis C virus (HCV) infection vary, and there were an estimated 1.75
million new cases worldwide in 2015. The World Health Organization aims for a 90 …
million new cases worldwide in 2015. The World Health Organization aims for a 90 …
Epidemiology and natural history of HCV infection
Abstract Worldwide, an estimated 130–170 million people have HCV infection. HCV
prevalence is highest in Egypt at> 10% of the general population and China has the most …
prevalence is highest in Egypt at> 10% of the general population and China has the most …
Human viral oncogenesis: a cancer hallmarks analysis
Approximately 12% of all human cancers are caused by oncoviruses. Human viral
oncogenesis is complex, and only a small percentage of the infected individuals develop …
oncogenesis is complex, and only a small percentage of the infected individuals develop …
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
T Kawai, S Akira - Immunity, 2011 - cell.com
Toll-like receptors (TLRs) are germline-encoded pattern recognition receptors (PRRs) that
play a central role in host cell recognition and responses to microbial pathogens. TLR …
play a central role in host cell recognition and responses to microbial pathogens. TLR …
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
Exhausted T cells express multiple co-inhibitory molecules that impair their function and limit
immunity to chronic viral infection. Defining novel markers of exhaustion is important both for …
immunity to chronic viral infection. Defining novel markers of exhaustion is important both for …
Pathogenic mechanisms in HBV-and HCV-associated hepatocellular carcinoma
A Arzumanyan, HM Reis, MA Feitelson - Nature Reviews Cancer, 2013 - nature.com
Hepatocellular carcinoma (HCC) is a highly lethal cancer, with increasing worldwide
incidence, that is mainly associated with chronic hepatitis B virus (HBV) and/or hepatitis C …
incidence, that is mainly associated with chronic hepatitis B virus (HBV) and/or hepatitis C …
Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis
D Saadoun, M Rosenzwajg, F Joly, A Six… - … England Journal of …, 2011 - Mass Medical Soc
Background Patients with vasculitis induced by the hepatitis C virus (HCV) have reduced
levels of regulatory T cells (Tregs). Resolution of HCV infection correlates with cure of …
levels of regulatory T cells (Tregs). Resolution of HCV infection correlates with cure of …
Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells
B Rehermann - Nature medicine, 2013 - nature.com
Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections account for 57% of
cases of liver cirrhosis and 78% of cases of primary liver cancer worldwide and cause a …
cases of liver cirrhosis and 78% of cases of primary liver cancer worldwide and cause a …