[HTML][HTML] Targeting ferroptosis in acute kidney injury

L Ni, C Yuan, X Wu - Cell Death & Disease, 2022 - nature.com
Acute kidney injury (AKI) is a major public health problem with high incidence and mortality.
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …

[HTML][HTML] The road from AKI to CKD: molecular mechanisms and therapeutic targets of ferroptosis

R Guo, J Duan, S Pan, F Cheng, Y Qiao, Q Feng… - Cell death & …, 2023 - nature.com
Acute kidney injury (AKI) is a prevalent pathological condition that is characterized by a
precipitous decline in renal function. In recent years, a growing body of studies have …

[HTML][HTML] Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5/6 nephrectomy-induced CKD rat model

J Wang, Y Wang, Y Liu, X Cai, X Huang, W Fu… - Cell death …, 2022 - nature.com
Ferroptosis is a non-traditional form of regulated cell death, characterized by iron overload
and lipid peroxidation. Exploration of ferroptosis in chronic kidney disease (CKD) has been …

[HTML][HTML] Ferroptosis and acute kidney injury (AKI): molecular mechanisms and therapeutic potentials

Q Feng, X Yu, Y Qiao, S Pan, R Wang… - Frontiers in …, 2022 - frontiersin.org
Acute kidney injury (AKI), a common and serious clinical kidney syndrome with high
incidence and mortality, is caused by multiple pathogenic factors, such as ischemia …

Small extracellular vesicles delivering lncRNA WAC-AS1 aggravate renal allograft ischemia‒reperfusion injury by inducing ferroptosis propagation

X Li, X Peng, X Zhou, M Li, G Chen, W Shi… - Cell Death & …, 2023 - nature.com
Ferroptosis is a predominant contributor to renal ischemia reperfusion injury (IRI) after
kidney transplant, evoking delayed graft function and poorer long-term outcomes. The wide …

A journey of challenges and victories: a bibliometric worldview of nanomedicine since the 21st century

J Wang, W Zhao, Z Zhang, X Liu, T Xie… - Advanced …, 2024 - Wiley Online Library
Nanotechnology profoundly affects the advancement of medicine. Limitations in diagnosing
and treating cancer and chronic diseases promote the growth of nanomedicine. However …

[HTML][HTML] Mitochondria bridge HIF signaling and ferroptosis blockage in acute kidney injury

W Li, Z Xiang, Y Xing, S Li, S Shi - Cell death & disease, 2022 - nature.com
Ferroptosis, a form of regulated cell death, plays an important role in acute kidney injury
(AKI). Previous studies have shown that prolyl hydroxylase domain protein (PHD) inhibitors …

The role of ferroptosis in the development of acute and chronic kidney diseases

Y Zhou, J Zhang, Q Guan, X Tao… - Journal of cellular …, 2022 - Wiley Online Library
Ferroptosis, a novel form of regulated cell death, is characterized by imbalance of
intracellular iron and redox systems, resulting from overgeneration of toxic lipid peroxidation …

[HTML][HTML] Vitexin attenuates chronic kidney disease by inhibiting renal tubular epithelial cell ferroptosis via NRF2 activation

J Song, H Wang, J Sheng, W Zhang, J Lei, W Gan… - Molecular …, 2023 - Springer
Background Chronic kidney disease (CKD) involves a variety of pathological processes, and
ferroptosis plays a vital role in CKD progression. Targeting ferroptosis is a promising …

Inhibition of ferroptosis ameliorates hypertensive nephropathy through p53/Nrf2/p21 pathway by Taohongsiwu decoction: based on network pharmacology and …

T Xie, Z Bai, Z Chen, H Liang, T Liu, LK Lam… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Hypertensive nephropathy (HN) is a complication of
hypertension. Taohongsiwu decoction (THSWD) is used clinically but its application in the …