Synthesis of novel tylophorine derivatives and evaluation of their anti-inflammatory activity

T Wen, Z Wang, X Meng, M Wu, Y Li, X Wu… - ACS Medicinal …, 2014 - ACS Publications
We have previously demonstrated that DCB-3503, a tylophorine analogue, has an anti-
inflammatory property in murine models for autoimmune diseases. However, its mechanism …

Design, synthesis, antiviral activity, and structure–activity relationships (SARs) of two types of structurally novel phenanthroindo/quinolizidine analogues

B Su, F Chen, L Wang, Q Wang - Journal of agricultural and food …, 2014 - ACS Publications
To investigate the influence of the variation of the original skeletons of natural
phenanthroindo/quinolizidine alkaloids on antiviral activities, two types of structurally totally …

Oxidative Cyclization Reaction of 2‐Aryl‐Substituted Cinnamates To Form Phenanthrene Carboxylates by Using MoCl5

K Wehming, M Schubert… - … A European Journal, 2014 - Wiley Online Library
The oxidative cyclization reaction of 2‐aryl cinnamates and derivatives thereof can be easily
performed with MoCl5 as the oxidant. This powerful reagent allows oxidative coupling …

Total Synthesis of (+)‐Antofine and (–)‐Cryptopleurine

W Ying, JW Herndon - European journal of organic chemistry, 2013 - Wiley Online Library
The tylophorine alkaloid anticancer compounds antofine and cryptopleurine have been
synthesized in optically active form. Both syntheses use optically pure α‐amino acids as the …

MoV Reagents in Organic Synthesis

M Schubert, SR Waldvogel - European Journal of Organic …, 2016 - Wiley Online Library
The use of MoV reagents, and in particular MoCl5, in organic synthesis is surveyed. The
oxidative treatment of aromatic substrates is the most common application. The unique …

Design, synthesis, antiviral activity and mode of action of phenanthrene‐containing N‐heterocyclic compounds inspired by the phenanthroindolizidine alkaloid …

X Yu, P Wei, Z Wang, Y Liu, L Wang… - Pest Management …, 2016 - Wiley Online Library
BACKGROUND The phenanthroindolizidine alkaloid antofine and its analogues have
excellent antiviral activity against tobacco mosaic virus (TMV). To simplify the structure and …

[HTML][HTML] Antiviral activity and mechanism of gossypols: effects of the O 2˙− production rate and the chirality

B Zhang, Y Liu, Z Wang, Y Li, Q Wang - RSC advances, 2017 - pubs.rsc.org
(−)-Gossypol displayed an obviously higher antiviral activity against the tobacco mosaic
virus (TMV) than (+)-gossypol, whereas the anti-TMV activity of (−)-gossypol Schiff bases is …

Synthesis and antiphytoviral activity of α-aminophosphonates containing 3, 5-diphenyl-2-isoxazoline as potential papaya ringspot virus inhibitors

ZG Zeng, N Liu, F Lin, XY Jiang, HH Xu - Molecular Diversity, 2019 - Springer
Abstract α-Aminophosphonates compounds containing 3, 5-diphenyl-2-isoxazoline were
synthesized and evaluated for their bioactivity. Seventeen of them showed good bioactivity …

Inhibitory effect of esterified lactoferin and lactoferin against tobacco mosaic virus (TMV) in tobacco seedlings

J Wang, HY Wang, XM Xia, P Li, KY Wang - Pesticide biochemistry and …, 2013 - Elsevier
The inhibitory effects of esterified lactoferrin (ELF) and lactoferrin (LF) against tobacco
mosaic virus (TMV) in tobacco seedlings and the underlying mechanism were investigated …

Synthesis of (–)‐Cryptopleurine by Combining Gold (I) Catalysis with a Free Radical Cyclization

A Stoye, T Opatz - European Journal of Organic Chemistry, 2015 - Wiley Online Library
Abstract (R)‐(–)‐Cryptopleurine, a highly cytotoxic alkaloid found in Cryptocarya and
Boehmeria species, was synthesized in high optical purity using a gold (I)‐NHC catalyzed …