The role of peripheral inflammatory insults in Alzheimer's disease: a review and research roadmap

KA Walker, LM Le Page, N Terrando… - Molecular …, 2023 - Springer
Peripheral inflammation, defined as inflammation that occurs outside the central nervous
system, is an age-related phenomenon that has been identified as a risk factor for …

White matter alterations in depressive disorder

E He, M Liu, S Gong, X Fu, Y Han, F Deng - Frontiers in Immunology, 2022 - frontiersin.org
Depressive disorder is the most prevalent affective disorder today. Depressive disorder has
been linked to changes in the white matter. White matter changes in depressive disorder …

Racial discrimination and white matter microstructure in trauma-exposed Black women

N Fani, NG Harnett, B Bradley, Y Mekawi, A Powers… - Biological …, 2022 - Elsevier
Background Experiences of racial discrimination are linked to a range of negative brain
health outcomes, but little is known about how these experiences impact neural architecture …

Extracellular vesicles from hiPSC-NSCs can prevent peripheral inflammation-induced cognitive dysfunction with inflammasome inhibition and improved neurogenesis …

G Ayyubova, M Kodali, R Upadhya, LN Madhu… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) released by human induced pluripotent stem cell-derived neural
stem cells (hiPSC-NSCs) are enriched with miRNAs and proteins capable of mediating …

Personality and Cognition: The Mediating Role of Inflammatory Markers

Y Stephan, AR Sutin, M Luchetti… - The Journals of …, 2024 - academic.oup.com
Abstract Objectives Five-Factor Model personality traits are associated consistently with
cognition. Inflammation has been hypothesized as a biological pathway in this association …

Complement protein levels in serum astrocyte-derived exosomes are associated with cognitive impairment in obstructive sleep apnea

M Li, C Sun, S Xue, B Leng, H Sun, T Shen… - Journal of Clinical …, 2023 - jcsm.aasm.org
Study Objectives: An association between neuroinflammation and cognitive decline has
been established. The complement system regulates neuroinflammation. Dysregulation …

Exploring relationships between alcohol consumption, inflammation, and brain structure in a heavy drinking sample

HC Karoly, CJ Skrzynski, EN Moe… - Alcoholism: Clinical …, 2021 - Wiley Online Library
Background Chronic alcohol consumption is associated with structural brain changes and
increased inflammatory signaling throughout the brain and body. Increased inflammation in …

[HTML][HTML] Adolescents at risk for depression show increased white matter microstructure with age across diffuse areas of the brain

H Sullivan-Toole, KR Jobson, LJ Hoffman… - Developmental …, 2023 - Elsevier
Maternal history of depression is a strong predictor of depression in offspring and linked to
structural and functional alterations in the developing brain. However, very little work has …

Adult atopic eczema and the risk of dementia: a population-based cohort study

A Magyari, M Ye, DJ Margolis, CE McCulloch… - Journal of the American …, 2022 - Elsevier
Background Chronic inflammatory conditions have been linked to dementia, but little is
known about the role of atopic eczema, an inflammatory condition recently recognized to be …

Association of poor oral health with neuroimaging markers of white matter injury in middle-aged participants in the UK Biobank

CA Rivier, DB Renedo, A de Havenon, NA Sunmonu… - Neurology, 2024 - AAN Enterprises
Background and Objectives Poor oral health is a modifiable risk factor that is associated with
clinically observed cardiovascular disease. However, the relationship between oral and …