Non-small cell lung cancer epigenomes exhibit altered DNA methylation in smokers and never-smokers

JA Karlow, EC Pehrsson, X Xing… - Genomics …, 2023 - academic.oup.com
Epigenetic alterations are widespread in cancer and can complement genetic alterations to
influence cancer progression and treatment outcome. To determine the potential …

Individualized chemotherapy guided by the expression of ERCC1, RRM1, TUBB3, TYMS and TOP2A genes versus classic chemotherapy in the treatment of breast …

J Li, P Sun, T Huang, S He, L Li… - Oncology …, 2021 - spandidos-publications.com
Abstract ERCC1, RRM1, TUBB3, TYMS and TOP2A genes have been shown to be
associated with drug resistance in various types of tumors; however, their roles in breast …

Clinical significance of UGT1A1 polymorphism and expression of ERCC1, BRCA1, TYMS, RRM1, TUBB3, STMN1 and TOP2A in gastric cancer

Y Cao, G Zhang, P Wang, J Zhou, W Gan, Y Song… - BMC …, 2017 - Springer
Background Individualized therapeutic regimen is a recently intensively pursued approach
for targeting diseases, in which the search for biomarkers was considered the first and most …

[HTML][HTML] Lung cancer transcriptomes refined with laser capture microdissection

J Lin, G Marquardt, N Mullapudi, T Wang, W Han… - The American journal of …, 2014 - Elsevier
We evaluated the importance of tumor cell selection for generating gene signatures in non–
small cell lung cancer. Tumor and nontumor tissue from macroscopically dissected (Macro) …

[PDF][PDF] 肺癌转移与中医脏象理论相关性分析

吕行, 宁鹏, 赵强, 张进儒, 江帆 - 现代生物医学进展, 2015 - biomed.cnjournals.com
摘要目的: 分析肺癌转移与中医脏象理论的相关性. 方法: 回顾性选择我院收治的102
例晚期肺癌转移患者为研究对象, 统计患者的转移灶所属部位, 并参照《 中医内科学》 …

Genome-Wide Epigenomic Profiling of Primary Non-Small Cell Lung Cancer Reveals Specific and Recurrent DNA Methylation Alterations in Smoker Versus Never …

JA Karlow, EC Pehrsson, X Xing, M Watson… - bioRxiv, 2022 - biorxiv.org
Epigenetic alterations are widespread in cancer and can complement genetic alterations to
influence cancer progression and treatment. To better understand the potential contribution …

Extensive analysis of the molecular biomarkers excision repair cross complementing 1, ribonucleotide reductase M1, β-tubulin III, thymidylate synthetase, and …

J Li, P Sun, T Huang, S He, L Li, G Xue - Medicine, 2021 - journals.lww.com
Excision repair cross complementing 1 (ERCC1), ribonucleotide reductase M1 (RRM1), β-
tubulin III (TUBB3), thymidylate synthetase (TYMS), and topoisomerase IIα (TOP2A) genes …

HER2 and PTEN as Predictive Markers for Breast Cancer Neoadjuvant Chemotherapy with Anthracycline Plus Paclitaxel

X Yang, XL Feng, X Wang, Y Fang… - Journal of Biomaterials …, 2016 - ingentaconnect.com
Anthracycline plus paclitaxel is frequently used as the care standard in neoadjuvant
chemotherapy for breast cancer patients, however its efficacy varies among individual …

The precise chemotherapy guided by the expression of ERCC1, RRM1, TUBB3, TYMS and TOP2A genes versus the classic chemotherapy in the treatment of breast …

LI Juncheng, P Sun, T Huang, S He, L Li, G Xue - 2019 - researchsquare.com
Objective: ERCC1, RRM1, TUBB3, TYMS and TOP2A gene have been shown to be
associated with chemotherapeutic drug resistance. And the aim of the present study was to …

Östrogenrezeptoren und ihre Bedeutung für die Prognose und Therapie des Lungenkarzinoms–neue Erkenntnisse zu einem bisher unterschätzten Mechanismus

WM Brückl, SE Al-Batran, JH Ficker, RM Wirtz… - …, 2015 - thieme-connect.com
Der Hauptrisikofaktor für die Entstehung von Lungenkarzinomen ist das Tabakrauchen,
jedoch erkranken zunehmend auch Nichtraucher an dieser Erkrankung, insbesondere …