Kidney disease is a significant health problem worldwide, affecting an estimated 10% of the
global population. Kidney disease encompasses a diverse group of disorders that vary in …

Mitochondria, widely known as the energy factories of eukaryotic cells, have a myriad of vital
functions across diverse cellular processes. Dysfunctions within mitochondria serve as …

Metabolic reprogramming to glycolysis is closely associated with the development of chronic
kidney disease (CKD). Although it has been reported that phosphofructokinase 1 (PFK) is a …

Abstract palmitoylation, a reversible post-translational modification, is initiated by the DHHC
family of palmitoyltransferases and reversed by several acyl protein thioesterases. However …

Multiple mechanisms are involved in kidney damage, among which the role of epigenetic
modifications in the occurrence and development of kidney diseases is constantly being …

Premature aging causes morphological and functional changes in the kidney, leading to
chronic kidney disease (CKD). CKD is a global public health issue with far-reaching …

Simple Summary Acute kidney injury is a common and severe group of clinical syndromes
with numerous causes, including sepsis. The molecular mechanisms underlying sepsis …

Sirtuins are a family of NAD+ III-dependent histone deacetylases that consists of seven
family members, Sirt1-Sirt7, which regulate various signalling pathways and are involved in …

Aims Diabetic kidney disease (DKD) is the one of the leading causes of end-stage kidney
disease. Unraveling novel biomarker signatures capable to identify patients with DKD is …

The functional and structural changes in the proximal tubule play an important role in the
occurrence and development of diabetic kidney disease (DKD). Diabetes-induced metabolic …