This review focuses on the potentials and perspectives of Locked Nucleic Acid (LNA)-based
oligonucleotides as therapeutic candidates. It briefly outlines various oligonucleotide-based …

The application of optical biosensors, specifically those that use optical fibers and planar
waveguides, has escalated throughout the years in many fields, including environmental …

Polyvalent oligonucleotide gold nanoparticle conjugates have unique fundamental
properties including distance-dependent plasmon coupling, enhanced binding affinity, and …

Locked nucleic acids (LNA; symbols of bases,+ A,+ C,+ G, and+ T) are introduced into
chemically synthesized oligonucleotides to increase duplex stability and specificity. To …

DNA is a unique material for nanotechnology since it is possible to use base sequences to
encode instructions for assembly in a predetermined fashion at the nanometre scale …

The naturally occurring nucleic acid bases (nucleobases) adenine, thymine (uracil),
guanine, and cytosine are widely appreciated for their ability to stabilize canonical Watson …

Peptide nucleic acid (PNA) is a DNA analog, in which the sugar-phosphate backbone in
DNA is replaced by poly [N-(2-aminoethyl) glycine]. Since its discovery in the early 1990s …

The design of peptide mimetic compounds is greatly facilitated by the identification of
functionalities that can act as peptide replacements. The fluoroalkene moiety has recently …

Structural DNA nanotechnology relies on Watson− Crick base pairing rules to assemble
DNA motifs into diverse arrangements of geometric shapes and patterns. While substantial …

Synthetic biology offers many new opportunities for the future. The increasing complexities
in engineering biological systems, however, also puts a burden on our abilities to judge the …