Treatment of unresectable stage III non-small cell lung cancer for patients who are under-represented in clinical trials

M Bortolot, F Cortiula, G Fasola, D De Ruysscher… - Cancer Treatment …, 2024 - Elsevier
Concurrent chemoradiotherapy (cCRT) followed by one year of consolidation durvalumab is
the current standard-of-care for patients with unresectable stage III non-small cell lung …

Beyond success: unveiling the hidden potential of radiotherapy and immunotherapy in solid tumors

Y Wu, M Yi, M Niu, B Zhou, Q Mei… - Cancer …, 2024 - Wiley Online Library
Immunotherapy, particularly with immune checkpoint inhibitors, has significantly transformed
cancer treatment. Despite its success, many patients struggle to respond adequately or …

Personalized Radiation Therapy—Spurning the “One Size Fits All” Approach

V Verma - JAMA oncology, 2023 - jamanetwork.com
The concepts of personalized medicine and personalized oncology are steadily gaining
steam in recent years. Yet, at times it may seem that personalized radiotherapy (RT) …

Evaluation of chest CT-scans following lung stereotactic ablative radiotherapy: Challenges and new insights

A De Bruycker, F Schneiders, S Gulstene… - Lung Cancer, 2024 - Elsevier
Stereotactic ablative radiotherapy (SABR) is increasingly used for the treatment of early-
stage non-small cell lung cancer (ES-NSCLC) and for pulmonary metastases. In patients …

First in Human Phase 1 Clinical Trial of Stereotactic Irradiation to Achieve Lung Volume Reduction (SILVR) in Severe Emphysema

DN Kamtam, MS Binkley, N Kapula, C Sadeghi… - International Journal of …, 2024 - Elsevier
Purpose Only a subset of patients with severe emphysema qualify for lung volume reduction
surgery or endobronchial valves. We previously demonstrated that stereotactic ablative …

[HTML][HTML] Optimizing Choice of Skin Surrogates for Surface-Guided Stereotactic Body Radiotherapy of Lung Lesions Using Four-Dimensional Computed Tomography

V Leipold, I Alerić, M Mlinarić, D Kosmina, F Stanić… - Cancers, 2024 - mdpi.com
Simple Summary Surface tracking based on optical cameras is often used to reduce the
imaging dose while maintaining precision during stereotactic ablative body radiotherapy. A …

[HTML][HTML] Multi-omics integrative modelling for stereotactic body radiotherapy in early-stage non-small cell lung cancer: clinical trial protocol of the MONDRIAN study

S Volpe, M Zaffaroni, G Piperno, MG Vincini… - BMC cancer, 2023 - Springer
Background Currently, main treatment strategies for early-stage non-small cell lung cancer
(ES-NSCLC) disease are surgery or stereotactic body radiation therapy (SBRT), with …

Histology-driven hypofractionated radiation therapy schemes for early-stage lung adenocarcinoma and squamous cell carcinoma

F Liu, MK Farris, JD Ververs, RT Hughes… - Radiotherapy and …, 2024 - Elsevier
Abstract Background and Purpose Histology was found to be an important prognostic factor
for local tumor control probability (TCP) after stereotactic body radiotherapy (SBRT) of early …

Pulmonary interstitial lymphography: A prospective trial with potential impact on stereotactic ablative radiotherapy planning for early-stage lung cancer

RB Ko, JA Abelson, D Fleischmann, JD Louie… - Radiotherapy and …, 2024 - Elsevier
This prospective feasibility trial investigated pulmonary interstitial lymphography to identify
thoracic primary nodal drainage (PND). A post-hoc analysis of nodal recurrences was …

Chest wall pain after single-fraction thoracic stereotactic ablative Radiotherapy: Dosimetric analysis from the iSABR trial

B Lau, YF Wu, S Cui, J Fu, S Jackson, D Pham… - Radiotherapy and …, 2024 - Elsevier
Abstract Background and Purpose Concerns over chest wall toxicity has led to debates on
treating tumors adjacent to the chest wall with single-fraction stereotactic ablative …