Population Pharmacokinetics of Intravenous Lidocaine in Adults: A Systematic Review
Background The establishment of optimal dosing regimens for intravenous (IV) lidocaine in
the perioperative setting, aiming to balance effective pain relief with minimisation of potential …
the perioperative setting, aiming to balance effective pain relief with minimisation of potential …
Comment on:“External evaluation of population pharmacokinetic models for precision dosing: current state and knowledge gaps”
M Lv, S Zhang - Clinical Pharmacokinetics, 2023 - Springer
We read with great interest the current opinion article by Mehdi El Hassani and Amélie
Marsot published in Clinical Pharmacokinetics journal [1], which described the current state …
Marsot published in Clinical Pharmacokinetics journal [1], which described the current state …
Performance of eight infliximab population pharmacokinetic models in a cohort of Dutch children with inflammatory bowel disease
NC Bevers, RJ Keizer, DR Wong, A Aliu… - Clinical …, 2024 - Springer
Abstract Background and Objective Efficacy of infliximab in children with inflammatory bowel
disease can be enhanced when serum concentrations are measured and further dosing is …
disease can be enhanced when serum concentrations are measured and further dosing is …
Multivariate Exact Discrepancy: A New Tool for PK/PD Model Evaluation
Background Pharmacokinetic models are evaluated using three types of metrics: those
based on estimating the typical pharmacokinetic parameters, those based on predicting …
based on estimating the typical pharmacokinetic parameters, those based on predicting …
Subgroup identification-based model selection to improve the predictive performance of individualized dosing
Currently, model-informed precision dosing uses one population pharmacokinetic model
that best fits the target population. We aimed to develop a subgroup identification-based …
that best fits the target population. We aimed to develop a subgroup identification-based …
Does Sample Size, Sampling Strategy, or Handling of Concentrations Below the Lower Limit of Quantification Matter When Externally Evaluating Population …
M El Hassani, U Liebchen, A Marsot - European Journal of Drug …, 2024 - Springer
Abstract Background and Objectives Precision dosing requires selecting the appropriate
population pharmacokinetic model, which can be assessed through external evaluations …
population pharmacokinetic model, which can be assessed through external evaluations …
Simulation-Based Optimization of Sampling Schedules for Model-Informed Precision Dosing of Once-Daily and 4-Times-Daily Busulfan in Pediatric Patients
Background: Therapeutic drug monitoring (TDM) is crucial in optimizing the outcomes of
hematopoietic stem cell transplantation by guiding busulfan (Bu) dosing. Limited sampling …
hematopoietic stem cell transplantation by guiding busulfan (Bu) dosing. Limited sampling …
Predictive Performance of a Gentamicin Pharmacokinetic Model in Term Neonates with Perinatal Asphyxia Undergoing Controlled Therapeutic Hypothermia
MAA van der Veer, TR de Haan… - Therapeutic drug …, 2022 - journals.lww.com
Background: Model validation procedures are crucial when population pharmacokinetic
(PK) models are used to develop dosing algorithms and to perform model-informed …
(PK) models are used to develop dosing algorithms and to perform model-informed …
[引用][C] Authors' Reply to Lv et al.:“External Evaluation of Population Pharmacokinetic Models for Precision Dosing: Current State and Knowledge Gaps”
M El Hassani, A Marsot - Clinical Pharmacokinetics, 2023 - Springer
We thank Meng Lv and Shengnan Zhang for their insightful comments and suggestions [1]
on our Current Opinion article titled “External Evaluation of Population Pharmacokinetic …
on our Current Opinion article titled “External Evaluation of Population Pharmacokinetic …