[HTML][HTML] mRNA vaccine in gastrointestinal tumors: Immunomodulatory effects and immunotherapy

A Zhang, Q Ji, X Sheng, H Wu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Gastrointestinal tumors remain a significant healthcare burden worldwide, necessitating the
development of innovative therapeutic strategies. mRNA vaccines have emerged as a …

Pathways and molecules for overcoming immunotolerance in metastatic gastrointestinal tumors

Q Gan, Y Li, Y Li, H Liu, D Chen, L Liu… - Frontiers in …, 2024 - frontiersin.org
Worldwide, gastrointestinal (GI) cancer is recognized as one of the leading malignancies
diagnosed in both genders, with mortality largely attributed to metastatic dissemination. It …

Hypoxia Affects Mitochondrial Stress and Facilitates Tumor Metastasis of Colorectal Cancer Through Slug SUMOylation

J Wang, S Ding, X Liu, T Yu, Z Wu… - Current Molecular …, 2024 - ingentaconnect.com
Background: Colorectal cancer (CRC) is a malignant tumor. Slug has been found to display
a key role in diversified cancers, but its relevant regulatory mechanisms in CRC …

[HTML][HTML] Mitochondria-targeted photodynamic therapy triggers GSDME-mediated pyroptosis and sensitizes anti-PD-1 therapy in colorectal cancer

Y Zhou, W Zhang, B Wang, P Wang, D Li… - … for ImmunoTherapy of …, 2024 - jitc.bmj.com
Background The effectiveness of immune checkpoint inhibitors in colorectal cancer (CRC) is
limited due to the low tumor neoantigen load and low immune infiltration in most …

Caffeic acid phenethyl ester promotes oxaliplatin sensitization in colon cancer by inhibiting autophagy

F Xing, N Liu, C Wang, XD Wang - 2023 - researchsquare.com
Colorectal cancer ranks as the third most prevalent form of cancer globally, with
chemotherapy remaining the primary treatment modality. To mitigate drug resistance and …