Distinct regions harboring cancer stem cells (CSCs) have been identified within the
microenvironment of various tumors, and as in the case of their healthy counterparts, these …

Cancer stem cells (CSCs) are tumor cells that have the principal properties of self-renewal,
clonal tumor initiation capacity, and clonal long-term repopulation potential. CSCs reside in …

There is increasing evidence that malignant tumors are initiated and maintained by a sub-
population of tumor cells that have similar biological properties to normal adult stem cells …

Dormancy occurs when cells remain viable but stop proliferating. When most of a cancer
population undergoes this phenomenon, the result is called tumor dormancy, and when a …

Despite recent progresses in tumor therapy and increased knowledge in tumor biology,
tumor remains a common and lethal disease worldwide. Cancer stem cells (CSCs) are a …

Cancer stem cell (CSC) biology and tumor immunology have shaped our understanding of
tumorigenesis. However, we still do not fully understand why tumors can be contained but …

Simple Summary Clear cell renal cell carcinoma (ccRCC) progression, which is the most
common form of kidney cancer, is associated with the loss of the Von Hippel-Lindau (VHL) …

A small proportion of cancer cells that have stem cell-like properties are known as cancer
stem cells (CSCs). They can be used to identify malignant tumor phenotypes and patients …

In embryonic development and throughout life, there are some cells can exhibit phenotypic
plasticity. Phenotypic plasticity is the ability of cells to differentiate into multiple lineages. In …

In different biological model systems, exosomes are considered mediators of cell‐cell
communication between different cell populations. Exosomes, as extracellular vesicles …