The DEAD-box helicase family member DDX3X (DBX, DDX3) functions in nearly all stages
of RNA metabolism and participates in the progression of many diseases, including virus …

From sites of transcription in the nucleus to the outreaches of the cytoplasm, messenger
RNAs are associated with RNA-binding proteins. These proteins influence pre-mRNA …

▪ Abstract The compartmentation of eukaryotic cells requires all nuclear proteins to be
imported from the cytoplasm, whereas, for example, transfer RNAs, messenger RNAs, and …

Animal cells have recently been shown to express a range of∼ 22 nucleotide noncoding
RNAs termed micro RNAs (miRNAs). Here, we show that the human mir-30 miRNA can be …

SUMMARY A defining characteristic of eukaryotic cells is the possession of a nuclear
envelope. Transport of macromolecules between the nuclear and cytoplasmic compartments …

Genome-wide transcriptional profiling of human epithelial cells revealed that repression of Id
inhibitors of differentiation (Id1, Id2, and Id3) is a general feature of the TGFβ cytostatic …

Increasing a protein concentration in solution to the required level, without causing
aggregation and precipitation is often a challenging but important task, especially in the field …

In eukaryotic cells, segregation of DNA replication and RNA biogenesis in the nucleus and
protein synthesis in the cytoplasm poses the requirement of transporting thousands of …

The only mammalian RNA binding adapter proteins known to partner with TAP/NXF1, the
primary receptor for general mRNA export, are members of the REF family. We demonstrate …

In eukaryotic cells, the enclosure of the genetic information in the nucleus allows the spatial
and temporal separation of DNA replication and transcription from cytoplasmic protein …