Moonlighting chromatin: when DNA escapes nuclear control

J Singh, M Boettcher, M Dölling, A Heuer… - Cell Death & …, 2023 - nature.com
Extracellular chromatin, for example in the form of neutrophil extracellular traps (NETs), is an
important element that propels the pathological progression of a plethora of diseases. DNA …

Bacterial extracellular vesicles: An emerging postbiotic

J Xie, Q Li, S Nie - Trends in Food Science & Technology, 2023 - Elsevier
Background Our growing appreciation of the functional significance of the human microbiota
in health and disease has triggered a marked interest in bacterial-derived extracellular …

Maternal microbiota communicates with the fetus through microbiota-derived extracellular vesicles

A Kaisanlahti, J Turunen, N Byts, A Samoylenko, G Bart… - Microbiome, 2023 - Springer
Background Reports regarding the presence of bacteria in the fetal environment remain
limited and controversial. Recently, extracellular vesicles secreted by the human gut …

Transformable nano-antibiotics for mechanotherapy and immune activation against drug-resistant Gram-negative bacteria

RS Li, J Liu, C Wen, Y Shi, J Ling, Q Cao, L Wang… - Science …, 2023 - science.org
The dearth of antibiotic candidates against Gram-negative bacteria and the rise of antibiotic
resistance create a global health concern. The challenge lies in the unique Gram-negative …

[HTML][HTML] Fusobacterium nucleatum outer membrane vesicles activate autophagy to promote oral cancer metastasis

G Chen, C Gao, S Jiang, Q Cai, R Li, Q Sun… - Journal of Advanced …, 2024 - Elsevier
Introduction Metastasis is an important cause of high mortality and lethality of oral cancer.
Fusobacterium nucleatum (Fn) can promote tumour metastasis. Outer membrane vesicles …

Lipopolysaccharide delivery systems in innate immunity

J Liu, R Kang, D Tang - Trends in Immunology, 2024 - cell.com
Lipopolysaccharide (LPS), a key component of the outer membrane in Gram-negative
bacteria (GNB), is widely recognized for its crucial role in mammalian innate immunity and …

The role of bacterial membrane vesicles in antibiotic resistance

CR MacNair, MW Tan - Annals of the New York Academy of …, 2023 - Wiley Online Library
Bacterial survival during antibiotic exposure is a complex and multifaceted phenomenon. On
top of antibiotic resistance genes, biofilm formation, and persister tolerance, bacterial …

Roles of extracellular vesicles in periodontal homeostasis and their therapeutic potential

DK Deng, JJ Zhang, D Gan, JK Zou, RX Wu… - Journal of …, 2022 - Springer
Periodontal tissue is a highly dynamic and frequently stimulated area where homeostasis is
easily destroyed, leading to proinflammatory periodontal diseases. Bacteria–bacteria and …

Desulfovibrio fairfieldensis-Derived Outer Membrane Vesicles Damage Epithelial Barrier and Induce Inflammation and Pyroptosis in Macrophages

Y Nie, XQ Xie, L Zhou, Q Guan, Y Ren, Y Mao, JS Shi… - Cells, 2022 - mdpi.com
Sulfate-reducing bacteria Desulfovibrio fairfieldensis is an opportunistic pathogen that
widely exists in the human intestine and can cause severe infectious diseases. However, the …

Bacterial extracellular vesicles control murine norovirus infection through modulation of antiviral immune responses

S Bhar, G Zhao, JD Bartel, H Sterchele… - Frontiers in …, 2022 - frontiersin.org
Human norovirus is the primary cause of non-bacterial gastroenteritis globally and is the
second leading cause of diarrheal deaths in children in developing countries. However …